[HTML][HTML] Disentangling ERBB signaling in breast cancer subtypes—A model-based analysis
S Kemmer, M Berdiel-Acer, E Reinz, J Sonntag… - Cancers, 2022 - mdpi.com
… the ERBB signaling network … the ERBB signaling network as displayed in Figure 2. Reaction
kinetics were modeled by the law of mass-action according to chemical reaction network …
kinetics were modeled by the law of mass-action according to chemical reaction network …
[HTML][HTML] The ErbB signaling network and its potential role in endometrial cancer
G Androutsopoulos, I Styliara, E Zarogianni, N Lazurko… - Epigenomes, 2023 - mdpi.com
… Some of these pathways are part of the EGF system signaling network, which becomes …
Our aim is to provide an update on current knowledge of the signaling network of ErbB …
Our aim is to provide an update on current knowledge of the signaling network of ErbB …
[HTML][HTML] HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B
DC Kirouac, J Du, J Lahdenranta… - PLoS computational …, 2016 - journals.plos.org
… This is a non-trivial task given the molecular and genetic heterogeneity of the disease,
and the complexity of cell signaling networks. As a result, the majority of patients treated with …
and the complexity of cell signaling networks. As a result, the majority of patients treated with …
EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms
B Van Lengerich, C Agnew… - Proceedings of the …, 2017 - National Acad Sciences
… for their signaling. Different ligands can activate these receptor pairs but lead to divergent …
We also show that HER receptor ligands exert unique effects on signaling by modulating …
We also show that HER receptor ligands exert unique effects on signaling by modulating …
[PDF][PDF] Disentangling ERBB Signaling in Breast Cancer Subtypes—A Model-Based Analysis. Cancers 2022, 14, 2379
S Kemmer, M Berdiel-Acer, E Reinz, J Sonntag… - 2022 - academia.edu
… the ERBB signaling network … the ERBB signaling network as displayed in Figure 2. Reaction
kinetics were modeled by the law of mass-action according to chemical reaction network …
kinetics were modeled by the law of mass-action according to chemical reaction network …
[HTML][HTML] Homo-and heteroassociations drive activation of ErbB3
… Dimerization or the formation of higher-order oligomers is required for the activation of ErbB
receptor … Untangling the ErbB signalling network. … Untangling the ErbB signalling network. …
receptor … Untangling the ErbB signalling network. … Untangling the ErbB signalling network. …
Growth factor–dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools
Y Brüggemann, LS Karajannis, A Stanoev… - … Signaling, 2021 - science.org
… The ErbB signaling network coordinates fundamental, often opposing cellular responses,
such as proliferation and differentiation, and thus functions as important context-dependent …
such as proliferation and differentiation, and thus functions as important context-dependent …
[HTML][HTML] Quantitative phosphoproteomics analysis of ERBB3/ERBB4 signaling
SK Wandinger, I Lahortiga, K Jacobs, M Klammer… - PLoS …, 2016 - journals.plos.org
… In this analysis, the KEGG term ‘ErbB signaling pathway’ reached the highest significance
consistent with cellular signaling induced through the EGFR family receptors ERBB3 and …
consistent with cellular signaling induced through the EGFR family receptors ERBB3 and …
Antitumour immunity regulated by aberrant ERBB family signalling
S Kumagai, S Koyama, H Nishikawa - Nature Reviews Cancer, 2021 - nature.com
… Oncogenic alterations of genes encoding members of the ERBB family, leading to aberrant
ERBB signalling and driving tumour growth, have been reported in various types of cancer …
ERBB signalling and driving tumour growth, have been reported in various types of cancer …
ErbB receptors and cancer
Z Wang - ErbB receptor signaling: methods and protocols, 2017 - Springer
… of Downstream Signaling Proteins and the Control of Cell Functions ErbB signaling networks
consist … By regulating these signaling networks, ErbB receptors govern fundamental cellular …
consist … By regulating these signaling networks, ErbB receptors govern fundamental cellular …