A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping
C Earl, C Bagnéris, K Zeman, A Cole… - Nucleic Acids …, 2018 - academic.oup.com
… -5], herpes simplex virus type 1 (HSV-1) [HHV-1] and human, … ×His tag and Tobacco Etch
Virus (TEV) protease recognition … (NEB), before recording changes in fluorescence due to the …
Virus (TEV) protease recognition … (NEB), before recording changes in fluorescence due to the …
[HTML][HTML] The essential co-option of Uracil-DNA Glycosylases by Herpesviruses invites novel antiviral design
R Savva - Microorganisms, 2020 - mdpi.com
… drug design activity on the conserved uracil-DNA glycosylases encoded by diverse
herpesviruses. The specific differences between the uracil-DNA glycosylase enzymes encoded by …
herpesviruses. The specific differences between the uracil-DNA glycosylase enzymes encoded by …
Is uracil-DNA glycosylase UNG2 a new cellular weapon against HIV-1?
… Focher F, Verri A, Verzeletti S, Mazzarello P, Spadari S… Uracil in OriS of herpes simplex
1 alters its specific recognition by origin binding protein (OBP): Does virus induced …
1 alters its specific recognition by origin binding protein (OBP): Does virus induced …
Herpesvirus DNA polymerases: Structures, functions and inhibitors
… of viral DNA polymerases of herpes simplex virus (HSV) and … the binding of homodimer of
UL9 origin binding protein to the … encoded by UL23 gene, uracil DNA glycosylase encoded by …
UL9 origin binding protein to the … encoded by UL23 gene, uracil DNA glycosylase encoded by …
Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells
EC Hansen, M Ransom, JR Hesselberth, NN Hosmane… - Elife, 2016 - elifesciences.org
… eLife digest Human immunodeficiency virus type 1 (HIV-1) … uracil, indicating that uracil
incorporation is specific to HIV … This result indicates that uracilation does not significantly alter …
incorporation is specific to HIV … This result indicates that uracilation does not significantly alter …
DNA-dependent DNA polymerases as drug targets in herpesviruses and poxviruses
J Luczkowiak, M Álvarez, A Sebastián-Martín… - Viral Polymerases, 2019 - Elsevier
… Taking as a reference the herpes simplex virus (HSV), the first … This origin binding protein
binds ssDNA in a nonspecific … of two proteins A20 and D4 and has intrinsic uracil DNA …
binds ssDNA in a nonspecific … of two proteins A20 and D4 and has intrinsic uracil DNA …
[HTML][HTML] HSV-1 DNA replication—coordinated regulation by viral and cellular factors
JE Packard, JA Dembowski - Viruses, 2021 - mdpi.com
… step in the herpes simplex virus type 1 (HSV-1) life cycle that … and OriS serve as binding
sites for the origin binding protein … As evidence for BER, HSV-1 codes for the uracil glycosylase …
sites for the origin binding protein … As evidence for BER, HSV-1 codes for the uracil glycosylase …
Impact of ATP-dependent RNA Helicase DDX3X on Herpes Simplex Type 1 (HSV-1) Replication
B Khadivjam - 2017 - papyrus.bib.umontreal.ca
… , the virus changes the localization of DDX3X and causes its … factor 1 (HCF-1) and
octamer-binding protein 1 (OCT1) binds … identification of up to 49 cellular proteins in Herpes …
octamer-binding protein 1 (OCT1) binds … identification of up to 49 cellular proteins in Herpes …
Functional analysis of multiple activities associated with the herpes simplex virus-1 DNA polymerase
JL Lawler - 2018 - search.proquest.com
… Upon infection, HSV-1 causes quick and dramatic changes … SSB binding, surrounded by
recognition sites for the origin-… of the single-stranded DNA binding protein ICP8, were variable …
recognition sites for the origin-… of the single-stranded DNA binding protein ICP8, were variable …
Kaposi's sarcoma-associated herpesvirus modulates the unfolded protein response during lytic replication
BP Johnston - 2020 - dalspace.library.dal.ca
… heat shoc( protein HSV-1 herpes simplex virus 1 HSV-2 … X box binding protein 1 (XBP1)
was identified 15 years before its mRNA was identified …
was identified 15 years before its mRNA was identified …