Clinical implications of uric acid in heart failure: a comprehensive review

M Kumrić, JA Borovac, TT Kurir, J Božić - Life, 2021 - mdpi.com
… Specifically, in this review we focused on uric acid (UA), a purine metabolism detriment … we
focused on uric acid (UA), a purine metabolism detriment whose role as a cardiovascular risk …

Serum uric acid, predicts heart failure in a large Italian cohort: search for a cut-off value the URic acid Right for heArt Health study

ML Muiesan, M Salvetti, A Virdis, S Masi… - Journal of …, 2021 - journals.lww.com
… of uric acid on the future development of heart failure in … uric acid and incident heart failure,
both by using uric acid as a continuous variable or by evaluating different degrees of uric acid

Uric acid and xanthine oxidase in heart failure—Emerging data and therapeutic implications

W Doehner, EA Jankowska, J Springer… - International journal of …, 2016 - Elsevier
cardiovascular risk factor has exhaustingly been debated for decades. While the association
of elevated uric acid (UA) levels with increased mortality … (including metabolic, inflammatory …

The importance of including uric acid in the definition of metabolic syndrome when assessing the mortality risk

…, Working Group on Uric Acid and Cardiovascular … - Clinical Research in …, 2021 - Springer
… Using a previously validated cardiovascular SUA cut-off to … We considered cardiovascular
mortality (CVM) at the end of … infarction, heart failure (HF) or stroke and sudden cardiac death. …

Prognostic value of serum uric acid in patients with acute heart failure: A meta-analysis

G Huang, J Qin, X Deng, G Luo, D Yu, M Zhang… - Medicine, 2019 - journals.lww.com
… of serum uric acid (SUA) in patients with acute heart failure (… the prognostic significance of
SUA level in patients with AHF. … Uric acid is a product of the metabolic breakdown of purine …

… -cause and cardiovascular mortality independently of hypertriglyceridemia in cardiometabolic patients without established CV disease: a sub-analysis of the URic acid …

A Mengozzi, NR Pugliese, G Desideri, S Masi, F Angeli… - Metabolites, 2023 - mdpi.com
URic acid Right for heArt Health (URRAH) study cohort who were followed for over 20 years
and had no established cardiovascular disease or uncontrolled metabolic disease. … validate

[HTML][HTML] Serum uric acid and risk of chronic heart failure: a systematic review and meta-analysis

L Miao, M Guo, D Pan, P Chen, Z Chen, J Gao… - Frontiers in …, 2021 - frontiersin.org
… in CHF progression is not yet clear, it is speculated to be: (i) Functional upregulation of a
key enzyme in purine metabolism, xanthine oxidase (XO), which derives reactive oxygen …

… uric acid and outcomes in patients with chronic heart failure through the whole spectrum of ejection fraction phenotypes: Analysis of the ESC-EORP Heart Failure …

G Ambrosio, MGC Leiro, LH Lund, S Coiro… - European Journal of …, 2021 - Elsevier
… elevated serum uric acid (sUA) predicts poor outcome in heart failure (HF). Uric acid can
contribute … (HF) is a heterogeneous clinical syndrome, associated with a spectrum of metabolic

Uric acid and sodium-glucose cotransporter-2 inhibition with empagliflozin in heart failure with reduced ejection fraction: the EMPEROR-reduced trial

W Doehner, SD Anker, J Butler, F Zannad… - European Heart …, 2022 - academic.oup.com
… is a common finding in patients with heart failure (HF) that is … , higher ventricular filling
pressure, and lower cardiac output. … metabolic syndrome, were not related to elevated SUA. The …

[HTML][HTML] Serum uric acid predicts incident metabolic syndrome in the elderly in an analysis of the Brisighella Heart Study

AFG Cicero, F Fogacci, M Giovannini, E Grandi… - Scientific reports, 2018 - nature.com
uric acid before a diagnosis of ischaemic heart disease 7 . There is also a growing evidence
that SUA is involved in metabolic … position and by the use of a validated oscillometric device, …