… Cancer-induced bone pain literature … understand the pain that may develop prior to detection
or in response to treatments, we need to integrate the animal models most commonly used …

… important tool for understanding the underlying mechanisms of … The first murine model of
localized cancer-induced bone pain … Mouse experiments were approved by the Danish Animal …

… the use of animal models of cancer pain, with a focus on cancer-induced bone pain (CIBP) …
remodelling, is critical to understanding the structural and neuronal mechanisms underlying …

… a more complete understanding of this unique pain state at the cellular level that may
allow for future development of mechanism-based treatments for cancer-induced bone pain. …

… been made in understanding CIBP, with studies published on … model, which for CIBP has
been done using an animal model… bone-derived pain models, including CIBP and the adjacent …

… Metastatic cancer-induced bone pain (CIBP) is a type of chronic pain with unique and …
Animal studies have reported the efficacy of α2δ subunit ligands in CIBP models, as well. In …

… , all animal models of cancer induced bone pain involved systemic injection of cancer cells
into animals, which caused severe deterioration of animal … challenge in understanding the …

… on collagen-induced arthritis in mouse model in our center [15]. … mouse model and evaluate
the mechanism of bone pain by … challenge in understanding the mechanism of cancer pain is …

… Here, a rodent model of cancer-induced bone pain (CIBP) was generated following syngeneic
rat … Animal models of bone cancer are essential for better understanding of the underlying …

… Although the etiology of cancer pain remains unclear, animal models of CIBP have unraveled
… To understand the pathology of the complex state of CIBP, it is essential to determine how …