Evaluating the application of chronic heart failure therapies and developing treatments in individuals with recent myocardial infarction: a review

J Harrington, MC Petrie, SD Anker, DL Bhatt… - JAMA …, 2022 - jamanetwork.com
… HF and post-MI trials of sacubitril-valsartan. Similarly, multiple trials of early and aggressive
use of therapies effective in chronic heart failure immediately post-MI failed to demonstrate …

Effect of sacubitril–valsartan on left ventricular remodeling in patients with acute myocardial infarction after primary percutaneous coronary intervention: a systematic …

Y Liu, Y Sun, W Dai - Frontiers in Pharmacology, 2024 - frontiersin.org
… left ventricular remodeling post-myocardial infarction is correlated to the risk of heart failure
(HF), which … Third, this study emphasizes that timely use of relevant drugs in patients with AMI …

Cardiovascular drugs approved for heart failure with reduced ejection fraction and/or post-myocardial infarction exert consistent effects in both populations: A meta …

C Dasaro, A Haslam, V Prasad - medRxiv, 2024 - medrxiv.org
… In 147 contrast, two drugs (sacubitril-valsartan and losartan) were compared against active
controls in 148 both HFrEF and post-MI. Of note, only sacubitril-valsartan used two distinct …

… mineralocorticoid receptor antagonists the Cinderella in evidence-based treatment of myocardial infarction complicated with heart failure? Lessons from PARADISE …

B Pitt, JP Ferreira, F Zannad - European Heart Journal, 2022 - academic.oup.com
… of heart failure (HF) in the early post-myocardial infarction (MI… and cardiovascular mortality6
and that sacubitril/valsartan could be … antagonist pattern of use in heart failure with reduced …

[HTML][HTML] Optimal treatment for post-MI heart failure in rats: dapagliflozin first, adding sacubitril-valsartan 2 weeks later

W Tao, X Yang, Q Zhang, S Bi, Z Yao - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Post-myocardial infarction heart failure (post-MI HF) is a common, life-threatening complication
in patients … All data in this study were used to determine the means and SDs. Student's t …

Effect of neprilysin inhibition on left ventricular remodeling in patients with asymptomatic left ventricular systolic dysfunction late after myocardial infarction

KF Docherty, RT Campbell, KJM Brooksbank… - Circulation, 2021 - Am Heart Assoc
infarction are at a high risk of developing heart failure. The … sacubitril/valsartan 97/103 mg
twice daily with valsartan 160 … A strength of the present trial was the use of valsartan as the …

Cardioprotective effects of LCZ696 (sacubitril/valsartan) after experimental acute myocardial infarction

M Ishii, K Kaikita, K Sato, D Sueta, K Fujisue… - Basic to Translational …, 2017 - jacc.org
… (sacubitril/valsartan) can lower the risk of cardiovascular events in chronic heart failure. …
patients with acute myocardial infarction (MI). The present study shows that LCZ696 can prevent …

… of sacubitril/valsartan in the PARADIGM-HF trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) …

N Okumura, PS Jhund, J Gong… - … : Heart Failure, 2016 - Am Heart Assoc
patients randomly assigned to sacubitril/valsartan, versus enalapril, according to background
use … Because β-blockers were used in the vast majority of patients, we could not carry out a …

[HTML][HTML] Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach

O Iborra-Egea, C Gálvez-Montón, S Roura… - … and applications, 2017 - nature.com
… for Sacubitril/Valsartan in heart failure and post-myocardial infarction remodeling, using an
… myocardial infarction in swine was analyzed to address post-infarction ventricular remodeling…

Development of Heart Failure in High-Risk Post-Myocardial Infarction Patients: An Analysis of the Paradise-MI Trial

P VanDer Meer, E Braunwald, MA Pfeffer, C Granger… - Circulation, 2023 - Am Heart Assoc
… mortality after high-risk acute myocardial infarction (AMI) and ii) compare the effects of
sacubitril/valsartan with the ACE inhibitor ramipril across heart failure (HF) risk categories. …