The role of angiotensin receptor–neprilysin inhibitors in cardiovascular disease—existing evidence, knowledge gaps, and future directions

AP Ambrosy, RJ Mentz, M Fiuzat… - … of heart failure, 2018 - Wiley Online Library
… evaluate the role of sacubitril/valsartan in CVD and to discuss … ), post-myocardial infarction
(MI), and hypertension (Table 3). … explore the application of sacubitril/valsartan in routine …

Effect of sacubitril/valsartan on biomarkers of extracellular matrix regulation in patients with HFpEF

JW Cunningham, BL Claggett, E O'Meara… - Journal of the American …, 2020 - jacc.org
heart failure with preserved ejection fraction. Given the biochemical targets of sacubitril/valsartan
beta-blocker use at baseline. Within the biomarker substudy, baseline characteristics of …

Sacubitril/valsartan ameliorates cardiac function and ventricular remodeling in CHF rats via the inhibition of the tryptophan/kynurenine metabolism and inflammation

J Gan, Y Wang, Y Deng, J Zhang, S Wang, X Jiang… - Scientific Reports, 2024 - nature.com
… The rat model of post-myocardial infarction CHF was induced by left anterior descending (…
Sacubitril/valsartan is a widely used medication for the treatment of heart failure and is …

The effects of angiotensin receptor-neprilysin inhibition on major coronary events in patients with acute myocardial infarction: insights from the PARADISE-MI trial

R Mehran, PG Steg, MA Pfeffer, K Jering, B Claggett… - Circulation, 2022 - Am Heart Assoc
… /valsartan on coronary outcomes in patients with AMI. … labeling for sacubitril/valsartan for
use in patients with chronic HF … heart disease, we conducted a sensitivity analysis substituting …

Cost‐effectiveness analysis of sacubitril/valsartan for the treatment of heart failure with reduced ejection fraction in the United States

PM Zueger, VM Kumar, RL Harrington… - … : The Journal of …, 2018 - Wiley Online Library
… the post-myocardial infarction HF population, with some estimates as low as $11,393/QALY
gained.43, 44 Nonpharmacologic therapies such as cardiac … , our model used a substantially …

Amelioration of cardiac dysfunction and ventricular remodeling after myocardial infarction by danhong injection are critically contributed by anti-TGF-β-mediated …

J Chen, W Cao, PF Asare, M Lv, Y Zhu, L Li… - Journal of …, 2016 - Elsevier
used to treat cardiovascular disease, it remains unknown whether DHI has an effect of delaying
the ventricular remodeling after myocardial infarction… DHI and valsartan treatment. Loose …

Entresto, a new panacea for heart failure?

P Khalil, G Kabbach, S Said… - Cardiovascular & …, 2018 - ingentaconnect.com
… of heart failure (PIONEERHF); or post-myocardial infarction (… has been in use as well for
heart failure patients and is also … patients with advanced heart failure compared to Valsartan. …

[引用][C] PostMyocardial Infarction Risk Stratification and Management

T Hill, V Menon - Manual of Cardiovascular Medicine, 2018 - Lippincott Williams & Wilkins

Clinical outcomes in patients with acute decompensated heart failure randomly assigned to sacubitril/valsartan or enalapril in the PIONEER-HF trial

DA Morrow, EJ Velazquez, AD DeVore, AS Desai… - Circulation, 2019 - Am Heart Assoc
… inhibitor sacubitril/valsartan reduces the rate of cardiovascular death or … the use of
sacubitril/valsartan to treat patients with … of sacubitril/valsartan among patients hospitalized for …

Sacubitril/valsartan: from clinical trials to real-world experience

JM Joly, AS Desai - Current Treatment Options in Cardiovascular …, 2018 - Springer
use of angiotensin-receptor blocker and neprilysin inhibitor sacubitril/valsartan to treat patients
with heart failure … : NCT02924727) is randomizing patients post myocardial infarction (MI) …