Clinical and immunological effects of p53-targeting vaccines
… include p53 peptides, viral vectors, and dendritic cells pulsed … Under cellular stress, p53
becomes activated and stabilized to … p53- and PADRE-peptide–pulsed autologous DCs. Before …
becomes activated and stabilized to … p53- and PADRE-peptide–pulsed autologous DCs. Before …
Combination of p53-DC vaccine and rAd-p53 gene therapy induced CTLs cytotoxic against p53-deleted human prostate cancer cells in vitro
H Saito, K Kitagawa, T Yoneda, Y Fukui… - Cancer Gene …, 2017 - nature.com
… Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization
in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-…
in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-…
Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer
Z Ding, Q Li, R Zhang, L Xie, Y Shu, S Gao… - Signal transduction and …, 2021 - nature.com
… neoantigen peptide-pulsed autologous DC vaccine and … The number of mutations in the
TP53 gene ranks at the top, … Eventually, the Neo-DCVac stabilized the patient’s condition …
TP53 gene ranks at the top, … Eventually, the Neo-DCVac stabilized the patient’s condition …
Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12
TL Slatter, M Wilson, C Tang, HG Campbell… - …, 2016 - Taylor & Francis
… and intravenous pulsed dendritic cells in high recurrence risk ovarian … Vaccination with
p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 …
p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 …
Trial watch: dendritic cell vaccination for cancer immunotherapy
J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
… targets for the development of anticancer vaccines. DC-based anticancer vaccination relies
on patient-derived DCs pulsed with a source of tumor-associated antigens (TAAs) in the …
on patient-derived DCs pulsed with a source of tumor-associated antigens (TAAs) in the …
Gene-modified dendritic cell vaccines for cancer
RS Abraham, DA Mitchell - Cytotherapy, 2016 - Elsevier
… -tumor effect than the peptide-pulsed DCs, corresponding with … In one trial, small cell lung
cancer patients received p53-… experience suggests that disease stabilization and prolonged …
cancer patients received p53-… experience suggests that disease stabilization and prolonged …
Alpha-type-1 polarized dendritic cell-based vaccination in newly diagnosed high-grade glioma: a phase II clinical trial
K Mitsuya, Y Akiyama, A Iizuka, H Miyata… - Anticancer …, 2020 - ar.iiarjournals.org
… vaccines were continued until progressive disease (PD) was determined by immune-related
(… of HLA-A2 or A24 peptide-pulsed α-type-1 polarizing DC vaccines for the treatment of high-…
(… of HLA-A2 or A24 peptide-pulsed α-type-1 polarizing DC vaccines for the treatment of high-…
Development of Cell Technologies Based on Dendritic Cells for Immunotherapy of Oncological Diseases
V Kurilin, A Alshevskaya, S Sennikov - Biomedicines, 2024 - mdpi.com
… Immunotherapy using dendritic cell-based vaccination is a natural approach using the …
outcomes and address the challenges associated with dendritic cell vaccination. Neoantigens are …
outcomes and address the challenges associated with dendritic cell vaccination. Neoantigens are …
Promising new tools for targeting p53 mutant cancers: Humoral and cell-based immunotherapies
V Chasov, M Zaripov, R Mirgayazova… - Frontiers in …, 2021 - frontiersin.org
… involves the use of tumor vaccines made from autologous or … to electroporate immature
dendritic cells for subsequent co-… disulfide bridge for improved stabilization. When compared to …
dendritic cells for subsequent co-… disulfide bridge for improved stabilization. When compared to …
Dendritic cell vaccines in ovarian cancer
X Zhang, T He, Y Li, L Chen, H Liu, Y Wu… - Frontiers in …, 2021 - frontiersin.org
… II trial of the p53 peptide cancer vaccine and DC vaccine (16)… response (PR), disease
stabilization, and prolonged survival … -associated antigens used to load dendritic cell vaccines. …
stabilization, and prolonged survival … -associated antigens used to load dendritic cell vaccines. …