Design of novel orotransmucosal vaccine-delivery platforms using artificial intelligence

L Garcia-del Rio, P Diaz-Rodriguez… - European Journal of …, 2021 - Elsevier
… However, the development of suitable mucosal vaccines is extremely challenging, due to …
designing new vaccine delivery platforms. For infectious diseases’ vaccines these molecules …

Inducing mucosal IgA: a challenge for vaccine adjuvants and delivery systems

PN Boyaka - The Journal of Immunology, 2017 - journals.aai.org
… The efficacy of such vaccines relies on the identification and/or engineering of vaccine
delivery systems that improve vaccine delivery to the targeted anatomic sites and immune cells. …

Bacteriophage T4 nanoparticles for vaccine delivery against infectious diseases

P Tao, J Zhu, M Mahalingam, H Batra… - Advanced drug delivery …, 2019 - Elsevier
… an adjuvant-loaded vaccine delivery system, leading to robust … Recently, we have developed
a novel vaccine delivery system … This system therefore has the ability to co-deliver multiple …

Hydrogel nanoparticles and nanocomposites for nasal drug/vaccine delivery

S Salatin, J Barar, M Barzegar-Jalali, K Adibkia… - Archives of pharmacal …, 2016 - Springer
… ability to enhance the nasal delivery of peptide/protein drugs and vaccines compared to the
… hydrogel nanocomposites for drug/vaccine delivery through the intranasal administration. …

Advances in intranasal vaccine delivery: A promising non-invasive route of immunization

E Kehagia, P Papakyriakopoulou, G Valsami - Vaccine, 2023 - Elsevier
… Lipopeptides were tested as vaccine delivery systems and evaluated for their immunogenicity
against Group A Streptococcus. Their IN administration demonstrated that the appropriate …

Fluorinated redox-responsive poly (amidoamine) as a vaccine delivery system for antitumor immunotherapy

H Yuan, Y Yang, W Xue, Z Liu - ACS Biomaterials Science & …, 2018 - ACS Publications
… One of the current challenges in developing tumor vaccines lies in finding effective immune
adjuvants or vaccine delivery systems to assist tumor antigens to induce antitumor cellular …

Improved DNA vaccine delivery with needle-free injection systems

C Ledesma-Feliciano, R Chapman, JW Hooper… - Vaccines, 2023 - mdpi.com
vaccine against COVID-19, delivered exclusively with NFIS. In this review, we discuss physical
delivery methods for DNA vaccines … As is discussed, prophylactic DNA vaccines delivered …

[HTML][HTML] Chitosan non-particulate vaccine delivery systems

R Masimov, EK Wasan - Journal of Pharmacy & Pharmaceutical …, 2024 - ncbi.nlm.nih.gov
… -based delivery systems satisfy the five expectations of an effective vaccine delivery system
as … Therefore, chitosan and its derivatives should be considered in vaccine development …

Development of a nanogel-based nasal vaccine as a novel antigen delivery system

R Nakahashi-Ouchida, Y Yuki… - Expert Review of Vaccines, 2017 - Taylor & Francis
… ; and (2) mucosal vaccine delivery systems that include lipid-based or polymer-based particles
[Citation42]. In addition, mucosal vaccine delivery systems can be classified into two main …

[HTML][HTML] Potential of polymeric particles as future vaccine delivery systems/adjuvants for parenteral and non-parenteral immunization against tuberculosis: A …

F Khademi, M Derakhshan… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
… (TB) vaccine is necessity. However, the development of new subunit vaccines is faced with
concerns … To overcome such problems, polymers-based vaccine delivery systems have been …