… The developed and validated method proved to be … this study is that it did not include the
analysis of metabolites for the two drugs. Particularly for CBZ, the presence of active metabolites…

… drug addicts were analyzed for opiates and cocaine. Drugs … Cardiac blood was taken out
of the pericardial sac after … metabolite morphine was in the usual therapeutic range. The …

… four days in different fluids (such as cardiac blood, urine and pericardial fluid) and in tissues
(… and validation of a gas chromatography – mass spectrometry assay for opiates and cocaine …

… quantified by gas chromatography/mass spectrometry/nitrogen … and its metabolite and a
quetiapine metabolite were detected… validated liquid chromatography/tandem mass spectrometry …

… While there is limited information on the activity of SCRA metabolites on these receptors,
for simplicity in this thesis, the term SCRA will also include metabolites. In order to understand …

… cocaine might increase the probability of a methadone-related death are still to be comprehended
and are beyond the aims of the present study… by using validated methods routinely …

… two plasma metabolites, Ndesmethyl clozapine and clozapine N-oxide. The N-oxide metabolite
is … between clozapine and metabolite exposure and clozapine-associated cardiotoxicity. …

… a screening using chromatography–mass spectrometry (GC–MS). … process could increase
the sensitivity of the technique. A phase II metabolite of methandienone was recently analyzed …

… validate, due to irregular variation in postmortem body fluids (… based on gas chromatography
mass spectrometry (GC-MS), … the metaboloics method to analyze pericardial fluid to select …

… Screening, libraryassisted identification and validated … and oral fluid pharmacokinetics after
intravenous cocaine … blood by gas chromatography-mass spectrometry after headspace-solid …