[HTML][HTML] Over-expression of cyclooxygenase-2 in colorectal cancer patients
… Whereas, no significant change in COX-2 mRNA expression was observed between low
stages and high stages of CRC (p= 0.585). Also, there was no significant correlation between …
stages and high stages of CRC (p= 0.585). Also, there was no significant correlation between …
Low‐dose aspirin acetylates cyclooxygenase‐1 in human colorectal mucosa: implications for the chemoprevention of colorectal cancer
P Patrignani, A Sacco, C Sostres… - Clinical …, 2017 - Wiley Online Library
The mechanism of action of low‐dose aspirin in the prevention of colorectal … cyclooxygenase
(COX)‐1 acetylation at serine‐529 (AceCOX‐1), in blood platelets vs. colorectal mucosa, at …
(COX)‐1 acetylation at serine‐529 (AceCOX‐1), in blood platelets vs. colorectal mucosa, at …
[HTML][HTML] The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis in the model of experimental colorectal cancer
H Gungor, N Ilhan, H Eroksuz - Biomedicine & Pharmacotherapy, 2018 - Elsevier
… We think that a statistically insignificant increase in TIMP-2 levels in the DMH-induced CRC
is due to a secondary change towards the increased MMP-2 activity. In the present study, we …
is due to a secondary change towards the increased MMP-2 activity. In the present study, we …
A systematic review of the cyclooxygenase-2 (COX-2) expression in rectal cancer patients treated with preoperative radiotherapy or radiochemotherapy
… As a result, the expression of COX-2 is elevated in up to 90% of colorectal cancers. It has …
The initial step that aimed to change the treatment guidelines regarding rectal cancer were two …
The initial step that aimed to change the treatment guidelines regarding rectal cancer were two …
Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients
TSR Jensen, B Mahmood, MB Damm, MB Backe… - BMC …, 2018 - Springer
… Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from
patients with colorectal … by amiloride can therefore be an unrelated variation in salt intake in our …
patients with colorectal … by amiloride can therefore be an unrelated variation in salt intake in our …
Cyclooxygenase and lipoxygenase gene expression in the inflammogenesis of breast cancer
BM Kennedy, RE Harris - Inflammopharmacology, 2018 - Springer
… Nevertheless, in the TCGA dataset, expression levels of … for about 50% of the variability in
CYP19A1 among ER-positive … fraction of the variability in CYP19A1 expression was explained …
CYP19A1 among ER-positive … fraction of the variability in CYP19A1 expression was explained …
Understanding the interplay between COX-2 and hTERT in colorectal cancer using a multi-omics analysis
GD Ayiomamitis, G Notas, T Vasilakaki, A Tsavari… - Cancers, 2019 - mdpi.com
… Taken together, the data from our study provide a comprehensive understanding of the
interactions between cyclooxygenases and hTERT in colorectal cancer and may help guide …
interactions between cyclooxygenases and hTERT in colorectal cancer and may help guide …
Anti-inflammatory effects of enhanced recovery programs on early-stage colorectal cancer surgery
A Venara, E Duchalais, A Dariel, P Aubert… - World Journal of …, 2018 - Springer
… Genes studied were cyclooxygenase 1 and 2 (COX-1 and COX-2), microsomal … the
expression of these genes in the muscularis propria and found no change in COX-2 (p = …
expression of these genes in the muscularis propria and found no change in COX-2 (p = …
Prostaglandin E2/EP signaling in the tumor microenvironment of colorectal cancer
R Mizuno, K Kawada, Y Sakai - International journal of molecular …, 2019 - mdpi.com
… acids by the enzyme cyclooxygenase-2 (COX-2) and also play pleiotropic roles at inflammatory
sites [15,16]. For example, prostaglandin E2 (PGE2), a major cyclooxygenase product in …
sites [15,16]. For example, prostaglandin E2 (PGE2), a major cyclooxygenase product in …
[HTML][HTML] SerpinB3 upregulates the Cyclooxygenase-2/β-Catenin positive loop in colorectal cancer
L Terrin, M Agostini, M Ruvoletto, A Martini… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… , determining a change in the impedance signal. The Cell Index, reflecting the cell number
present in well, was monitored every 10 minutes and calculated as the relative change of …
present in well, was monitored every 10 minutes and calculated as the relative change of …