[HTML][HTML] Molecular mechanisms mediating antiangiogenic action of the urokinase receptor-derived peptide UPARANT in human retinal endothelial cells

C Motta, G Lupo, D Rusciano, M Olivieri… - … & Visual Science, 2016 - arvojournals.org
… ), and tight junction (TJ) expression at the protein and mRNA levels. Vascular endothelial
growth factor-related signaling molecules were also analyzed by Western and northern blots. …

The urokinase plasminogen activator system components are regulated by vascular endothelial growth factor D in bovine oviduct

DC García, A Russo-Maenza, DC Miceli… - Zygote, 2018 - cambridge.org
… members of the vascular endothelial growth factors (VEGF) and their receptors. In this study,
… VEGFR-2 is predominantly expressed by activated endothelia of blood vessels and VEGFR-…

[HTML][HTML] … proline-rich homeodomain protein (PRH) transcription factor activity and de-repressing vascular endothelial growth factor (VEGF) receptor expression

V Stepanova, PS Jayaraman, SV Zaitsev… - Journal of Biological …, 2016 - ASBMB
… function of the transcription factor hematopoietically expressed … activity of vehgr1 and vegfr2
gene promoters. These studies … that the urokinase receptor protects pro-urokinase against …

Vascular endothelial growth factor signaling in development and disease

S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular systems. …

[PDF][PDF] Vascular endothelial growth factor (VEGF)-key factor in normal and pathological angiogenesis

CS Melincovici, AB Boşca, S Şuşman… - Rom J Morphol …, 2018 - rjme.ro
… , placenta growth factor (PlGF), and, recently, to this family has been added endocrine gland-…
vascular endothelial growth factor (EG-VEGF). VEGF binds to tyrosine kinase cell receptors (…

[HTML][HTML] Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma …

C Ragone, M Minopoli, V Ingangi, G Botti… - Journal of Experimental …, 2017 - Springer
… evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration
through its assembly in composite regulatory units with transmembrane receptors, and uPAR …

Contribution of vascular endothelial growth factor receptor-2 sialylation to the process of angiogenesis

P Chiodelli, S Rezzola, C Urbinati, F Federici Signori… - Oncogene, 2017 - nature.com
Vascular endothelial growth factors (VEGFs) play a pivotal role in mediating the angiogenic
… and urokinase expression in vascular endothelial cells. J Cell Physiol 1994; 161: 1–14. …

Atorvastatin from target screening attenuates endothelial cell tube formation and migration by regulating urokinase receptor-related signaling pathway and F/G actin

L Wei, JS Chen, HT Lin, CZ Wu… - Journal of the …, 2017 - journals.lww.com
… Taken together, our findings suggest that Ator decreases mEC migration itself but not due
to … Our study is the first to suggest that Ator decreases F/G actin and expression of F-actin in …

[HTML][HTML] Endothelial biomarkers (Von willebrand factor, BDCA3, urokinase) as predictors of mortality in COVID-19 patients: cohort study

RN Sánchez-Santillán, MP Sierra-Vargas… - BMC Pulmonary …, 2024 - Springer
… cytokines, which increase platelet overproduction and release vascular endothelial growth
factor (VEGF); VEGF interacts with ECs, increasing the expression of tissular factor, which is …

[HTML][HTML] The urokinase receptor: a multifunctional receptor in cancer cell biology. therapeutic implications

A Li Santi, F Napolitano, N Montuori… - International journal of …, 2021 - mdpi.com
… tyrosine-kinases (RTK) as epidermal growth factor receptor (EGFR), platelet-derived growth
factor receptor (PDGFR) and insulin-like growth factor 1 receptor (IGFR) has been shown, …