Secreted Frizzled-Related Proteins 4 and 5: What They Are and Can They Be Used as a Biomarker in Gestational Diabetes Mellitus

RHJ Beernink, JHN Schuitemaker - Biomarkers in Diabetes, 2022 - Springer
… during pregnancy, the Wnt signaling pathway is also associated with … tyrosine phosphorylation
in skeletal muscle from obese … The Wnt antagonist and secreted frizzled-related protein 5: …

Frizzled related protein deficiency impairs muscle strength, gait and calpain 3 levels

L Casas-Fraile, FM Cornelis, D Costamagna… - Orphanet Journal of …, 2020 - Springer
… integrin interacting proteins as well as proteins implicated in … as a secreted antagonist of
the Wnt signalling pathway, … the effects of absence of Frzb in skeletal muscle of Frzb −/− mice, …

SFRP2 affects prenatal muscle development and is regulated by microRNA-1/206 in pigs

Y YANG, SUN Wei, Z Rong, LI Kui, Z TANG - Journal of Integrative …, 2016 - Elsevier
Secreted frizzled-related protein 2 (SFRP2), a member of the … It exhibited abundant expression
in prenatal skeletal muscle … Interaction of frizzled related protein (FRP) with Wnt ligands …

Secreted frizzled related protein 4 (sFRP4) update: A brief review

NM Pawar, P Rao - Cellular signalling, 2018 - Elsevier
… virtue of their regulatory function to the Wnt signal transduction system. … Functionally, wnt
antagonists can be divided into two classes, … In early pregnancy, the endometrium undergoes …

JARID2 and the PRC2 complex regulate skeletal muscle differentiation through regulation of canonical Wnt signaling

A Adhikari, J Davie - Epigenetics & chromatin, 2018 - Springer
… We show that the Wnt antagonist SFRP1 is highly … frizzled related protein 1 (Sfrp1) and
naked cuticle homolog … grown in DMEM supplemented with 10% fetal bovine serum (HyClone). …

Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice

LF de Castro, BJ Sworder, B Mui, K Futrega… - Bone research, 2021 - nature.com
… suggested that Sfrp2 is a Wnt antagonist. On the contrary, our data … 1, 2), demonstrating that
Sfrp2 is not essential for fetal or … In our in vitro experiments, Sfrp2 deficiency was associated

Tenotomy immobilization as a model to investigate skeletal muscle fibrosis (with emphasis on Secreted frizzled-related protein 2)

U Akpulat, İ Onbaşılar… - Physiological genomics, 2016 - journals.physiology.org
… Concomitantly, Sfrp2, a Wnt antagonist as well as a … Chronic muscle degeneration is a complex
process involving a … (I) collagen expression in fetal human intestinal smooth muscle cells. …

Association of secreted frizzled-related protein 4 with obesity and type II diabetes

MK Shrewastwa, V Acharya, AK Mahat - Nepal Medical Journal, 2022 - nmj.com.np
… regulate various functions from fetal growth to adulthood. … (b) In the presence of Wnt
antagonists that either bind to Wnts (… produce Wnt ligands, like secreted frizzled-related protein5 (…

Different balance of Wnt signaling in adult and fetal bone marrow-derived mesenchymal stromal cells

MM Paciejewska, MW Maijenburg… - Stem cells and …, 2016 - liebertpub.com
Secreted frizzled-related protein-4 (SFRP4), an inhibitor of … genes associated with limb and
skeletal muscle development; … Secreted frizzled related protein 1 regulates Wnt signaling for …

Secreted frizzled related proteins in cardiovascular and metabolic diseases

H Guan, J Zhang, J Luan, H Xu, Z Huang… - Frontiers in …, 2021 - frontiersin.org
… of Wnt proteins, a secreted protein that binds to Wnt protein … interaction between Wnt
antagonism and Wnt activation during … expressed at low levels in skeletal muscles and serum of …