… (b) erasers - a group of enzymes proficient in removing these marks, and (c) readers - a diverse
… epigenetic marks in a locus. These enzymes and protein domains together constitute the …

… ”), and subsequently recognized by effector proteins (“readers”). Most epigenetic marks are
reversible, and classes of enzymes (“erasers”) exist that remove these marks. The complex …

… -modifying enzymes, the writers and erasers of methylcytosine. … epigenetic marks are
maintained or, in some tissue types, progressively change. In many ways, these simple markers are …

… A limited repertoire of epigenetic modifications … epigenetic mechanism. It mainly occurs on
cytosines (5 mC, 5hmC, 5 fC, and 5caC) and is the most abundant and stable epigenetic mark …

… epigenetic mechanisms in atherosclerosis, with emphasis on the role of DNA and
chromatin-modifying writer-readereraser … changes in gene expression and epigenetic marks …

… thinking about how m 6 A readers, writers and erasers regulate the m 6 A epitranscriptome
… Localization of the m 6 A writer complex to H3K36me3 marks could confer site specificity in …

… with catalytic domains (writers, erasers, or ATPase remodelers) and … epigenetics biology,
focusing on the molecular mechanisms for the recognition of epigenetic marks by novel readers…

… Misplaced epigenetic marks are often found in cancerous cells. … in regulating these
marks. Each requires a writer to place it, an eraser to remove it and a reader to interpret it (see ‘…

… erasers can counter the writer's activities. The eraser can catalyze the removal of epigenetic
marks, thereby reducing the effect of epigenetic marks on transcription; thus, leading to …

… In addition, quercetin inhibited the expression of the epigenetic markers HDAC-1 and DNMT1
to induce cell cycle arrest and apoptosis, thereby blocking invasion and angiogenesis [133…