[HTML][HTML] Hallmarks of glycosylation in cancer

J Munkley, DJ Elliott - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aberrant glycosylation is often cited as a ‘hallmark of cancer’ … than aberrant glycosylation
being itself a hallmark of cancer, … that glycans play a role in every recognised cancer hallmark. …

Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
… on the pathophysiological implications of glycosylation. Fortunately, cutting-edge …
cancer-related glycosylation. Thus, glycans as well as aberrantly glycosylated protein-based cancer

Aberrant protein glycosylation in cancer: implications in targeted therapy

JG Rodrigues, HO Duarte, CA Reis… - Biochemical Society …, 2021 - portlandpress.com
… Furthermore, such aberrant glycan structures play key roles in the acquisition of molecular
… anti-cancer targeted agents. In this review, we highlight the impact of glycosylation in cancer

Epigenetic bases of aberrant glycosylation in cancer

F Dall'Olio, M Trinchera - International journal of molecular sciences, 2017 - mdpi.com
… in cancer. We see how different epigenetic mechanisms converge to regulate specific pathways
of cancer-… We also summarize the case of O-linked GlcNAc, in which glycosylation is not …

Glycosylation: a hallmark of cancer?

BN Vajaria, PS Patel - Glycoconjugate journal, 2017 - Springer
… remarkable progress in cancer research, … Aberrant glycosylation interferes with regulation
of cell adhesion, migration and proliferation. Glycosylation may represent a hallmark of cancer, …

Altered glycosylation in cancer: A promising target for biomarkers and therapeutics

D Thomas, AK Rathinavel, P Radhakrishnan - … (BBA)-Reviews on Cancer, 2021 - Elsevier
cancerglycosylation machinery is associated with cancer progression and metastasis. We
also provide insights into the influence of aberrant glycosylation in the development of cancer

Glyco-genes change expression in cancer through aberrant methylation

A Vojta, I Samaržija, L Bočkor, V Zoldoš - Biochimica et Biophysica Acta …, 2016 - Elsevier
… dysregulated in different cancers other than brain cancer. We also report for the first time
aberrant expression of the GALNT and MAN genes in cancer by aberrant promoter methylation. …

[HTML][HTML] Aberrant protein glycosylation: Implications on diagnosis and Immunotherapy

R Bangarh, C Khatana, S Kaur, A Sharma… - Biotechnology …, 2023 - Elsevier
… receptors lead to many diseases, including cancer. These alterations give rise to micro- …
glycosylation and its regulatory function in autoimmunity and aberrant glycosylation in cancer. …

Aberrant glycosylation in cancer: a novel molecular mechanism controlling metastasis

A Magalhães, HO Duarte, CA Reis - Cancer cell, 2017 - cell.com
Glycosylation alterations are involved in several steps of human cancer pathogenesis. In this
issue of Cancer Cell, Agrawal et al. identified the glycosyltransferase FUT8 as a previously …

[HTML][HTML] Glycosylation changes in cancer

SL Bellis, CA Reis, A Varki, R Kannagi, P Stanley - 2022 - europepmc.org
… Loss of polarization and overexpression of mucins displaying aberrant glycosylation has
made these glycoproteins a major source of biomarkers with clinical applications. The rod-like …