… as a protective mechanism to avoid cell-division when potentially damaged [30]. By
initiating cell-cycle arrest, cells can thus avoid cell division during stress and injury, which is …

… of the cell cycle following AKI and the markers of cell cycle arrest that enable the … kidney
disease (CKD) by regulating cell cycle arrest. Keywords: Acute kidney injury, cell cycle arrest, …

… chronic kidney disease; however, its role in acute kidney injury … the G1 cell cycle arrest of
tubular epithelial cells (TECs) in … into the kidney. In Smad7 gene knockout (KO) mice, more …

… acute kidney injury or reflect normal physiology. In this secondary analysis of the Sapphire
study, we examined biomarkers of cell cycle arrest … severe acute kidney injury (Kidney Disease…

… acute kidney injury stage 2–3, stage 1, or no acute kidney injury by Kidney Disease … %
had three or more exposures to a known renal insult. There was a significant association …

… If we compare AKI with acute coronary syndrome, in which an … kidney damage. Tissue
inhibitor of metalloproteinase 2 and insulin-like growth factor binding protein 7 are cell cycle arrest …

… signaling to cause tubular epithelial cell death and AKI via the G1 cell cycle arrest mechanism.
This is further confirmed in Smad3 knockout mice and cells in which deletion of Smad3 …

… potential biomarker of acute kidney injury (AKI). This meta-analysis aimed to evaluate the
predictive value of this biomarker for cardiac surgery-associated acute kidney injury (CSA-AKI). …

… Acute kidney injury (AKI) is a frequent complication in ICU patients [1]. AKI definitions based
on serum creatinine (sCr) have shown a large variation in AKI incidence and associated …

… Acute kidney injury (AKI) is a common disease in the intensive care unit (ICU). AKI patients
with nonrecovery of renal … the utility of urinary cell cycle arrest biomarkers for predicting …