Cystic fibrosis: recent insights into inhaled antibiotic treatment and future perspectives

G Taccetti, M Francalanci, G Pizzamiglio, B Messore… - Antibiotics, 2021 - mdpi.com
pulmonary exacerbations in CF. In this review, the efficacy and safety of the currently available
inhaled antibiotics … Moreover, the effects of long-term inhaled antibiotic therapy for chronic …

The pharmacokinetics of antibiotics in cystic fibrosis

AM Akkerman-Nijland, OW Akkerman… - Expert opinion on …, 2021 - Taylor & Francis
… The first report of inhaled antibiotic use in CF appeared in the … use of inhaled antibiotics in
the CF population. The development of inhaled antibiotics has primarily focused on antibiotics

Aerosolized antibiotics

J Dugernier, G Reychler, JC Dubus… - Clinical Pulmonary …, 2017 - journals.lww.com
… In conclusion, to definitively recommend treatment algorithms for inhaled antibiotics in
non–cystic fibrosis bronchiectasis large-scale, long-term controlled studies are needed. …

Aerosolized antibiotics for patients with bronchiectasis

TR Nadig, PA Flume - American Journal of Respiratory and Critical …, 2016 - atsjournals.org
inhaled antibiotics only after patients have suffered repeated exacerbations despite appropriate
use of chronic macrolides, aerosolized … trial of nebulized gentamicin in non-cystic fibrosis

The efficacy of inhaled antibiotics in non-cystic fibrosis bronchiectasis

R Amaro, M Panagiotarakou, V Alcaraz… - Expert Review of …, 2018 - Taylor & Francis
Inhaled antibiotics have been used for a long … inhaled antibiotics in NCFB patients.
Furthermore, we will address potential future challenges in the widespread use of inhaled antibiotics, …

Aerosolized agents for airway clearance in cystic fibrosis

KW Southern, JP Clancy… - Pediatric …, 2019 - Wiley Online Library
… In summary, dornase alfa, hypertonic saline, and mannitol are inhaled agents that have
each been shown to demonstrate pulmonary benefits in CF by improving mucus clearance, …

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis

S Smith, NJ Rowbotham… - Cochrane Database of …, 2022 - cochranelibrary.com
inhaled antibiotics for the treatment of pulmonary exacerbations in people with cystic
fibrosis… trial of inhaled antibiotics for the management of pulmonary exacerbations (NCT03066453). …

[HTML][HTML] The fate of inhaled antibiotics after deposition in cystic fibrosis: how to get drug to the bug?

AC Bos, KM Passé, JW Mouton, HM Janssens… - … of Cystic Fibrosis, 2017 - Elsevier
… with inhaled antibiotics, most commonly tobramycin, aztreonam and colistin. Deposition
patterns of inhaled antibiotics … However, after deposition in the airways, the antibiotic must first …

Current and Emerging Inhaled Antibiotics for Chronic Pulmonary Pseudomonas aeruginosa and Staphylococcus aureus Infections in Cystic Fibrosis

D Li, EK Schneider-Futschik - Antibiotics, 2023 - mdpi.com
… Additionally, inhaled liposomal amikacin and murepavadin are … inhaled antibiotics will
be summarized. Combination therapy and the strategies to select an optimal inhaled antibiotic

Aerosolized antibiotics for treatment of pneumonia in mechanically ventilated subjects

FJ Wong, T Dudney, R Dhand - Respiratory Care, 2019 - rc.rcjournal.com
… Experience with using inhaled antibiotics has varied. Aerosolized antibiotics have been …
patients with cystic fibrosis, tuberculosis, non-cystic fibrosis bronchiectasis, or COPD (Table 2). …