The treatment of the pulmonary and extrapulmonary manifestations of cystic fibrosis

M Chin, SD Aaron, SC Bell - La Presse Médicale, 2017 - Elsevier
Inhaled antibiotics are used in CF to eradicate new bacterial infections treating acute
pulmonary … The premise of inhaled antibiotics is to target the site of infection and decrease the …

Combining ivacaftor and intensive antibiotics achieves limited clearance of cystic fibrosis infections

SL Durfey, S Pipavath, A Li, AT Vo, A Ratjen, S Carter… - MBio, 2021 - Am Soc Microbiol
… Furthermore, the study was burdensome and difficult to expand beyond a single center, as
it required 3.5 months of IV, oral, and inhaled antibiotic treatment, immediate on-site sample …

Microbial contamination of home nebulizers in children with cystic fibrosis and clinical implication on the number of pulmonary exacerbations

SA Tabatabaii, G Khanbabaee, S Sadr… - BMC pulmonary …, 2020 - Springer
… In Iran, home administration of nebulized antibiotics is widespread as a treatment for children
with CF. To the best of our knowledge, no surveys of bacteriological contamination of these …

[HTML][HTML] Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients

J Rello, JJ Rouby, C Sole-Lleonart, J Chastre… - Clinical Microbiology …, 2017 - Elsevier
Nebulized antibiotics have an established role in patients with cystic fibrosis or … of evidence
of the therapeutic utility of aerosolized antibiotics in mechanically ventilated patients was …

[HTML][HTML] The clinical and microbiological utility of inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis: An open-label …

F Frost, GR Young, L Wright, N Miah, DL Smith… - … of Cystic Fibrosis, 2021 - Elsevier
… definitive trials of inhaled antibiotics in the acute setting. … Inhaled antibiotics are used
frequently in CF to target chronic P. … Little is known regarding the utility of inhaled antibiotics in the …

The effect of antibiotic changes during treatment of cystic fibrosis pulmonary exacerbations

A Zikic, F Ratjen, M Shaw, E Tullis, V Waters - Journal of Cystic Fibrosis, 2022 - Elsevier
… Changes included IV, oral and inhaled antibiotics. We did not assess inhaled antibiotic
changes. The reason for the antibiotic change was determined based on blinded review of …

Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis

C Sole-Lleonart, JJ Rouby, S Blot, G Poulakou… - …, 2017 - pubs.asahq.org
… Studies involving children, colonized-but-not-infected adults, and cystic fibrosis patients …
Our hypothesis was that nebulized antibiotics are safe and effective for therapy of nosocomial …

Combinations of colistin solutions and nebulisers for lung infection management in cystic fibrosis patients

F Buttini, I Rossi, M Di Cuia, A Rossi, G Colombo… - International Journal of …, 2016 - Elsevier
… deposition of the aerosol obtained from differently concentrated colistimethate sodium
solutions and nebulisers dictates the therapy design to the physician for cystic fibrosis patients. …

… of use of tobramycin inhalation powder compared with nebulized tobramycin and colistimethate sodium: a crossover study in cystic fibrosis patients with pulmonary …

J Greenwood, C Schwarz… - Therapeutic …, 2017 - journals.sagepub.com
… as an effective inhaled antibiotic for the treatment of chronic Pa pulmonary infection in …
pulmonary infection due to Pa in adult and pediatric CF patients. The administration of nebulized

An evaluation of inhaled antibiotic liposome versus antibiotic nanoplex in controlling infection in bronchiectasis

TT Tran, H Yu, C Vidaillac, AYH Lim… - International journal of …, 2019 - Elsevier
… A majority of bronchiectasis patients, with either cystic fibrosis (CF) … Inhaled antibiotics has
been proposed to have a role in … Inhaled antibiotics has been the mainstay of treatment for CF …