DNA methylation variability in Alzheimer's disease

Z Huo, Y Zhu, L Yu, J Yang, P De Jager, DA Bennett… - Neurobiology of …, 2019 - Elsevier
DNA methylation plays a critical role in brain aging and Alzheimer's disease (AD). While …
largely focused on testing mean DNA methylation, DNA methylation instability (quantified by …

DNA methylation in the pathology of Alzheimer's disease: from gene to cognition

CH Poon, LSR Tse, LW Lim - Annals of the New York Academy …, 2020 - Wiley Online Library
… Among epigenetic modifications, DNA methylation requires … of DNA methylation, the effects
of aberrant methylation on gene … , as well as memory epigenetics in Alzheimer's disease. …

[PDF][PDF] DNA methylation alterations in Alzheimer's disease

AS Yokoyama, JC Rutledge… - Environmental epigenetics, 2017 - academic.oup.com
DNA methylation, histone modifications and non-coding RNA, this review will focus specifically
on DNA methylation … in confirmed Alzheimer disease. Arch Neurol 1998;55: 1449–55. 41. …

[HTML][HTML] Altered mitochondrial DNA methylation pattern in Alzheimer disease–related pathology and in Parkinson disease

M Blanch, JL Mosquera, B Ansoleaga, I Ferrer… - The American journal of …, 2016 - Elsevier
… samples with Alzheimer disease-related … a dynamic pattern in the content of mitochondrial
5-methylcytosine in amyloid precursor protein/presenilin 1 mice along with Alzheimer disease

Association of peripheral blood DNA methylation level with Alzheimer's disease progression

…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2021 - Springer
… between DNA methylation at cytosine-… DNA methylation profiles measured using Infinium®
MethylationEPIC BeadChip and AD progression in participants from the Alzheimer’s Disease

Dynamic regulation of DNA methylation and brain functions

J Xie, L Xie, H Wei, XJ Li, L Lin - Biology, 2023 - mdpi.com
DNA methylation is involved in biological processes including neurogenesis, aging, and the
… A comprehensive understanding of dynamic DNA methylation changes during development …

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex

G Gasparoni, S Bultmann, P Lutsik, TFJ Kraus… - Epigenetics & …, 2018 - Springer
… the association analysis for Braak stage The aim of this study is to address DNA methylation
… Before starting our cell sorting approach, we performed an initial DNA methylation screen …

Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1

P Cronin, MJ McCarthy, ASP Lim, DP Salmon… - Alzheimer's & …, 2017 - Elsevier
… clock, and changes in DNA methylation have been reported in … We hypothesized that aberrant
DNA methylation may affect … Our results indicate that cycles of DNA methylation contribute …

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2020 - Springer
… Data collection and sharing for this project was funded by the Alzheimer's Disease
Neuroimaging Initiative (ADNI) (National Institutes of Health Grant U01 AG024904) and DOD ADNI (…

Epigenetics in Alzheimer's disease: perspective of DNA methylation

TJ Qazi, Z Quan, A Mir, H Qing - Molecular Neurobiology, 2018 - Springer
… (FAD), and autosomal dominant Alzheimer’s disease (ADAD). Down to the minutest of …
methylation patterns like mitochondrial DNA methylation and ribosomal DNA (rDNA) methylation. …