Synthesis of amphiphilic Janus dendrimer and its application in improvement of hydrophobic drugs solubility in aqueous media
F Najafi, M Salami-Kalajahi… - European Polymer …, 2020 - Elsevier
… dendrimers in drug delivery including solubility improvement of hydrophobic drugs, Janus
dendrimers are used to improve solubility … different generations of Janus dendrimers. Since the …
dendrimers are used to improve solubility … different generations of Janus dendrimers. Since the …
High-generation amphiphilic Janus-dendrimers as stabilizing agents for drug suspensions
M Selin, S Nummelin, J Deleu, J Ropponen… - …, 2018 - ACS Publications
… to stabilize drug suspensions of the poorly water-soluble drugs … by which amphiphilic JDs
stabilize pharmaceutical drug … adsorption kinetics of the JDs to drug crystals in suspension. …
stabilize pharmaceutical drug … adsorption kinetics of the JDs to drug crystals in suspension. …
An emerging class of amphiphilic dendrimers for pharmaceutical and biomedical applications: Janus amphiphilic dendrimers
DR Sikwal, RS Kalhapure, T Govender - European Journal of …, 2017 - Elsevier
… These dendrimers were capable of carrying multiple drug molecules and targeting the bone
… solubility compared to the native naproxen. This enhanced bone-affinity and solubility can …
… solubility compared to the native naproxen. This enhanced bone-affinity and solubility can …
[HTML][HTML] Properties and bioapplications of amphiphilic janus dendrimers: A Review
A Căta, IMC Ienașcu, MN Ştefănuț, D Roșu, OR Pop - Pharmaceutics, 2023 - mdpi.com
… water-soluble drug molecules. Amphiphilic Janus dendrimers can be adsorbed onto drug …
offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …
offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …
Janus-type dendrimers: Synthesis, properties, and applications
F Najafi, M Salami-Kalajahi… - Journal of Molecular …, 2022 - Elsevier
… Janus dendrimers have enhanced solubility, electrochemical … To improve the solubility of
hydrophobic drugs in water, … Two of the amphiphilic Janus dendrimers included galactose …
hydrophobic drugs in water, … Two of the amphiphilic Janus dendrimers included galactose …
Vesicles from amphiphilic dumbbells and janus dendrimers: Bioinspired self-assembled structures for biomedical applications
S Taabache, A Bertin - Polymers, 2017 - mdpi.com
… Vesicular structures as drug delivery systems (DDS) might help overcoming the
limitations of free drugs, such as poor water-solubility, severe side-effects due to a non-selective …
limitations of free drugs, such as poor water-solubility, severe side-effects due to a non-selective …
Self-assembly behavior of amphiphilic Janus dendrimers in water: a combined experimental and coarse-grained molecular dynamics simulation approach
ME Elizondo-García, V Márquez-Miranda… - Molecules, 2018 - mdpi.com
… and hydrophilic domains, reducing the overall solubility of the amphiphile. It is necessary to
… novel amphiphilic Janus dendrimers with assemblies adapted to be applied to drug delivery …
… novel amphiphilic Janus dendrimers with assemblies adapted to be applied to drug delivery …
Thermosensitive amphiphilic janus dendrimers with embedded metal binding sites. synthesis and self-assembly
X Liu, I Gitsov - Macromolecules, 2018 - ACS Publications
… ) dendrimers. Herein we report the creation of new family of amphiphilic Janus dendrimers
… The investigations on the application of these dendrimers in catalysis and drug delivery are …
… The investigations on the application of these dendrimers in catalysis and drug delivery are …
Nanostructures based on ammonium-terminated amphiphilic Janus dendrimers as camptothecin carriers with antiviral activity
A Lancelot, R Clavería-Gimeno… - European Polymer …, 2017 - Elsevier
… and hydrophilic dendrons, and this allows an evaluation of their compatibility with the
poorly-water soluble drug, CPT. The self-assembly in water and the morphology of the resulting …
poorly-water soluble drug, CPT. The self-assembly in water and the morphology of the resulting …
Enthalpy-driven self-assembly of amphiphilic Janus dendrimers into onion-like vesicles: a Janus particle model
FF Hu, YW Sun, YL Zhu, YN Huang, ZW Li, ZY Sun - Nanoscale, 2019 - pubs.rsc.org
… transportation of drugs, … amphiphilic Janus dendrimer solution into water or buffer. This is
important to make time for the self-assembly of dendrimers by transferring them from a soluble …
important to make time for the self-assembly of dendrimers by transferring them from a soluble …
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