Efficacy of repurposed antiviral drugs: lessons from COVID-19
MA Martinez - Drug Discovery Today, 2022 - Elsevier
… Several repurposed drugs have been assessed clinically, … New antiviral drugs targeting
different SARS-CoV-2 enzymes … will see the impact of these newly developed drugs on COVID-19…
different SARS-CoV-2 enzymes … will see the impact of these newly developed drugs on COVID-19…
[HTML][HTML] Antiretroviral drugs impact autophagy with toxic outcomes
L Cheney, JM Barbaro, JW Berman - Cells, 2021 - mdpi.com
… highlights the gaps in our knowledge of the impacts of antiretroviral drugs on autophagy. …
impact of antiretroviral drugs on autophagy as they relate to clinical side effects and toxicities. …
impact of antiretroviral drugs on autophagy as they relate to clinical side effects and toxicities. …
[HTML][HTML] Candidate antiviral drugs for COVID-19 and their environmental implications: a comprehensive analysis
… summarized the epidemiological and clinical data from several clinical trials conducted since
… The restrictions on travel and businesses significantly impacted the economic condition, …
… The restrictions on travel and businesses significantly impacted the economic condition, …
The importance of resistance to direct antiviral drugs in HCV infection in clinical practice
C Sarrazin - Journal of hepatology, 2016 - Elsevier
… time, susceptibility to additional antiviral agents is reduced or duration of treatment is
suboptimal. In this review geno- and phenotypic resistance testing as well as clinical data on the …
suboptimal. In this review geno- and phenotypic resistance testing as well as clinical data on the …
A review: Mechanism of action of antiviral drugs
S Kausar, F Said Khan… - International journal …, 2021 - journals.sagepub.com
… currently used antiviral drugs, mechanism of action and antiviral agents … potential have
been developed for clinical use for the treatment of … Antagonistic impacts of antiviral drugs …
been developed for clinical use for the treatment of … Antagonistic impacts of antiviral drugs …
[HTML][HTML] Direct acting anti-hepatitis C virus drugs: clinical pharmacology and future direction
A Geddawy, YF Ibrahim, NM Elbahie… - Journal of translational …, 2017 - degruyter.com
… The impact of drug-drug interaction depends upon many factors including the patient’s age,
sex, genomics… Drug-drug interactions during antiviral therapy for chronic hepatitis C. Nat Rev …
sex, genomics… Drug-drug interactions during antiviral therapy for chronic hepatitis C. Nat Rev …
Tissue distributions of antiviral drugs affect their capabilities of reducing viral loads in COVID-19 treatment
… Currently, many antiviral drugs have been tested in COVID-19 clinical trials and their
clinical … How potent the drugs are in vitro and how the drugs work might also impact on their …
clinical … How potent the drugs are in vitro and how the drugs work might also impact on their …
The impact of age on antiretroviral drug pharmacokinetics in the treatment of adults living with HIV
… of antiretroviral medications (ARVs), fewer drug regimens have … combination antiretroviral
therapies: conversely antiviral … in several antiretroviral drugs but the clinical relevance of …
therapies: conversely antiviral … in several antiretroviral drugs but the clinical relevance of …
The impact of direct‐acting antivirals on hepatitis C viraemia among people who inject drugs in England; real‐world data 2011–2018
M Bardsley, E Heinsbroek, R Harris… - Journal of viral …, 2021 - Wiley Online Library
… As countries push towards elimination goals, ‘real-world’ data on the impact of scaling up
HCV … We aim to assess the early impact of DAA scale-up in England by examining changes in …
HCV … We aim to assess the early impact of DAA scale-up in England by examining changes in …
Real‐world impact of direct acting antiviral therapy on health‐related quality of life in HIV/Hepatitis C co‐infected individuals
… Secondly, similar to the clinical trials we observed an immediate impact of HCV treatment
response, from baseline to response, albeit not as strong. However, assessing changes in …
response, from baseline to response, albeit not as strong. However, assessing changes in …
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