Dynamic changes of DNA methylation induced by benzo (a) pyrene in cancer
H Wang, B Liu, H Chen, P Xu, H Xue, J Yuan - Genes and Environment, 2023 - Springer
… hypermethylation, resulting in cancer initiation and progression. Here we summarized …
changes in DNA methylation in BaP exposure, and revealed the methylation of DNA plays a …
changes in DNA methylation in BaP exposure, and revealed the methylation of DNA plays a …
Epigenome-wide DNA methylation signature of benzo [a] pyrene exposure and their mediation roles in benzo [a] pyrene-associated lung cancer development
H Meng, G Li, W Wei, Y Bai, Y Feng, M Fu… - Journal of hazardous …, 2021 - Elsevier
… Our results highlight DNA methylation alterations as potential … -wide DNA methylation
changes associated with B[a]P exposure is still unknown and the extent to which DNA methylation …
changes associated with B[a]P exposure is still unknown and the extent to which DNA methylation …
Influence of benzo (a) pyrene on different epigenetic processes
B Bukowska, P Sicińska - International Journal of Molecular Sciences, 2021 - mdpi.com
… The results showed the tissue specificity of global DNA methylation, ie, the total genomic
DNA methylation level was significantly decreased in the blood and liver but not in the pancreas…
DNA methylation level was significantly decreased in the blood and liver but not in the pancreas…
Association of environmental benzo [a] pyrene exposure and DNA methylation alterations in hepatocellular carcinoma: a Chinese case–control study
M Tian, B Zhao, J Zhang, FL Martin, Q Huang… - Science of The Total …, 2016 - Elsevier
… risk factors [eg, benzo[a]pyrene (B[a]P), … , serum DNA methylation of TSGs was quantified
using high-resolution melting (HRM) analysis. Our results clearly indicate elevated methylation …
using high-resolution melting (HRM) analysis. Our results clearly indicate elevated methylation …
Embryonic exposure to benzo (a) pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation
D Gao, J Lin, K Ou, Y Chen, H Li, Q Dai, Z Yu… - Environmental …, 2018 - Elsevier
… hypermethylation of promoter DNA is generally related to gene silencing (Vandegehuchte
and Janssen, 2011). In this study, the DNA methylation … , since DNA methylation is heritable in …
and Janssen, 2011). In this study, the DNA methylation … , since DNA methylation is heritable in …
The effect of benzo [alpha] pyrene on DNA methylation and telomerase activity in human normal and cancer cells
… DNA methylation in human normal and cancer cells. … DNA methylation changes are two
hallmarks of cancer cells. Previous studies have demonstrated that the global DNA methylation …
hallmarks of cancer cells. Previous studies have demonstrated that the global DNA methylation …
Chronic administration of benzo (a) pyrene induces memory impairment and anxiety-like behavior and increases of NR2B DNA methylation
W Zhang, F Tian, J Zheng, S Li, M Qiang - PLoS One, 2016 - journals.plos.org
… , to assess the potential alteration of DNA methylation associated to BaP-induced neurobehavioral
performance. We found that the levels of DNA methylation in several CpG sites were …
performance. We found that the levels of DNA methylation in several CpG sites were …
The dual effects of Benzo (a) pyrene/Benzo (a) pyrene-7, 8-dihydrodiol-9, 10-epoxide on DNA Methylation
C Zhao, H Jin, Y Lei, Q Li, Y Zhang, Q Lu - Science of The Total …, 2024 - Elsevier
… ), BPDE can form DNA adducts, recruiting DNMT3 and leading to hypermethylation at specific
… of BaP/BPDE-induced DNA methylation changes and provide insights into future precision …
… of BaP/BPDE-induced DNA methylation changes and provide insights into future precision …
Paternal benzo [a] pyrene exposure alters the sperm DNA methylation levels of imprinting genes in F0 generation mice and their unexposed F1-2 male offspring
W Zhang, J Yang, Y Lv, S Li, M Qiang - Chemosphere, 2019 - Elsevier
… Benzo[a]pyrene (BaP) is an environmental pollutant known to cause teratogenesis. However…
Recently, the alteration of DNA methylation of imprinting genes has emerged as a specific …
Recently, the alteration of DNA methylation of imprinting genes has emerged as a specific …
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo [a] pyrene exposed F1 and F3 male medaka
… global methylation levels and decreased global DNA methylation … Reduced global DNA
methylation coupled with the … embryos, which suggests that DNA methylation may play a role in …
methylation coupled with the … embryos, which suggests that DNA methylation may play a role in …
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