DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans
B Hwa Yun, J Guo, M Bellamri… - Mass spectrometry …, 2020 - Wiley Online Library
… and biological effects of DNA adducts, and highlight our … of cells may be appropriate for
estimating exposure and DNA … , bulky aromatic DNA adduct levels in total white blood cells …
estimating exposure and DNA … , bulky aromatic DNA adduct levels in total white blood cells …
Linking the generation of DNA adducts to lung cancer
… At the current moment, there are some difficulties impeding the widespread use of adducts
in blood cells as a biomarker of lung cancer risk (Bak et al., 2006), conversely, we provide …
in blood cells as a biomarker of lung cancer risk (Bak et al., 2006), conversely, we provide …
Quantification of Hemoglobin and White Blood Cell DNA Adducts of the Tobacco Carcinogens 2-Amino-9H-pyrido[2,3-b]indole and 4-Aminobiphenyl Formed in …
T Cai, M Bellamri, X Ming, WP Koh, MC Yu… - Chemical research in …, 2017 - ACS Publications
… white blood cells (WBC) are another surrogate blood … genotoxicants primarily by screening
of DNA adducts with 32 P-… bulky aromatic type adducts in WBC DNA of smokers compared …
of DNA adducts with 32 P-… bulky aromatic type adducts in WBC DNA of smokers compared …
Linking DNA adduct formation and human cancer risk in chemical carcinogenesis
MC Poirier - Environmental and molecular mutagenesis, 2016 - Wiley Online Library
… and in nucleated blood cells; human DNA adduct formation … between the highest DNA adduct
levels in blood cells or target … when DNA adducts are measured either in blood cell DNA or …
levels in blood cells or target … when DNA adducts are measured either in blood cell DNA or …
Acrylamide-derived DNA adducts in human peripheral blood mononuclear cell DNA: correlation with body mass
M Hemgesberg, S Stegmüller, A Cartus… - Food and Chemical …, 2021 - Elsevier
… of AA-derived DNA adducts present in humans in … DNA adduct formation and carcinogenic
outcome is of outstanding interest. Here, we investigated the levels of the major DNA adduct …
outcome is of outstanding interest. Here, we investigated the levels of the major DNA adduct …
The relationship between exposure to airborne particulate and DNA adducts in blood cells in an urban population of subjects with an unhealthy body mass index
A Pulliero, S Iodice, AC Pesatori, L Vigna… - International Journal of …, 2022 - mdpi.com
… and repair DNA … DNA adducts in blood cells, in a population of 196 adults with an unhealthy
BMI (≥25). For each subject, a DNA sample was obtained for quantification of DNA adducts …
BMI (≥25). For each subject, a DNA sample was obtained for quantification of DNA adducts …
DNA adducts from anticancer drugs as candidate predictive markers for precision medicine
A Stornetta, M Zimmermann, GD Cimino… - Chemical research in …, 2017 - ACS Publications
… (106) This FA study was the first instance of low abundant cytotoxic G-NOR-G adducts
being measured in blood cells, underlying the sensitivity of HPLC-MS/MS approaches in the …
being measured in blood cells, underlying the sensitivity of HPLC-MS/MS approaches in the …
[HTML][HTML] Detection of BPDE-DNA adducts in human umbilical cord blood by LC-MS/MS analysis
L Guo, X Jiang, HY Tian, SJ Yao, BY Li… - journal of food and drug …, 2019 - Elsevier
… in umbilical cord white blood cells using the 32 P-postlabeling … exposure, measured by
DNA adducts, may adversely affect … -dG adducts in the DNA of umbilical cord white blood cell …
DNA adducts, may adversely affect … -dG adducts in the DNA of umbilical cord white blood cell …
DNA Adducts as Biomarkers To Predict, Prevent, and Diagnose Disease—Application of Analytical Chemistry to Clinical Investigations
C Hernandez-Castillo, J Termini… - Chemical Research in …, 2019 - ACS Publications
… induces DNA adducts, these are transported by blood and … of disease, such as DNA adducts,
from most major organs as … analyze adduct levels in DNA isolated from white blood cells …
from most major organs as … analyze adduct levels in DNA isolated from white blood cells …
DNA Adducts in Cancer Chemotherapy
Y Li - Journal of Medicinal Chemistry, 2024 - ACS Publications
… DNA adducts formed by the US FDA-approved drugs. Moreover, clinical studies on DNA
adducts … This suggests the potential of monitoring DNA adducts in patient blood cells to assess …
adducts … This suggests the potential of monitoring DNA adducts in patient blood cells to assess …
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