[HTML][HTML] The role of TNF in the pathogenesis of inflammatory bowel disease

M Perše, A Unkovič - … Therapy for Inflammatory Bowel Disease, 2019 - intechopen.com
Tumor necrosis factor (TNF) is a pleotropic cytokine involved in a wide range of pathological
processes, including inflammatory bowel disease (IBD). In the past, TNF was recognized as …

TNF-alpha blockers in inflammatory bowel diseases: practical recommendations and a user's guide: an update

M Vulliemoz, S Brand, P Juillerat, C Mottet… - Digestion, 2020 - karger.com
… (anti-TNF) antagonists have been the mainstay in the treatment of inflammatory bowel
diseases (… Summary: This review article aimed to provide an update on recent advances in TNF

local tumor necrosis factor-α inhibition in inflammatory bowel disease

B Gareb, AT Otten, HW Frijlink, G Dijkstra… - Pharmaceutics, 2020 - mdpi.com
… (Crohn’s disease OR inflammatory bowel disease OR ulcerative … (tumor necrosis factor OR
tumor necrosis factor-alpha OR TNF) AND (Crohn’s disease OR inflammatory bowel disease

[HTML][HTML] Study of tumor necrosis factor receptor in the inflammatory bowel disease

RF Souza, MAF Caetano, HIR Magalhães… - World Journal of …, 2023 - ncbi.nlm.nih.gov
… of disease remission in most patients[24,30]. This review aims to provide the main aspects
of IBD and TNF-α relationship, elucidating the role of the TNF-α receptors, anti TNF-α therapy …

Long-term safety ofin uteroexposure to anti-TNFα drugs for the treatment of inflammatory bowel disease: Results from the multicenter European TEDDY study

…, A Peixoto, G Martin, A Armuzzi, A Garre… - Official journal of the …, 2018 - journals.lww.com
… Anti-tumor necrosis factor α (anti-TNFα) drugs have been increasingly used for the treatment
of IBD ( 5 ). Therefore, many women wishing to become pregnant may be exposed to these …

Combining anti-TNF-α and vedolizumab in the treatment of inflammatory bowel disease: a case series

LCT Buer, ML Høivik, DJ Warren… - … Bowel Diseases, 2018 - academic.oup.com
… Anti-tumor necrosis factor α (anti-TNF-α) is important in the treatment of inflammatory bowel
disease, … In these patients, a combination of anti-TNF-α and vedolizumab (VDZ) may act as a …

Loss of response to anti‐TNFα agents depends on treatment duration in patients with inflammatory bowel disease

JPD Schultheiss, R Mahmoud… - Alimentary …, 2021 - Wiley Online Library
α (anti-TNFα) agents are widely used as maintenance treatment for patients with inflammatory
bowel disease … of a subsequent loss of response to anti-TNFα has been estimated to be as …

Optimizing anti-TNF-α therapy: serum levels of infliximab and adalimumab are associated with mucosal healing in patients with inflammatory bowel diseases

B Ungar, I Levy, Y Yavne, M Yavzori, O Picard… - Clinical …, 2016 - Elsevier
… It is not clear what serum levels of anti–tumor necrosis factor are associated with reduced
intestinal inflammation in patients with inflammatory bowel disease (IBD). We aimed to identify …

[PDF][PDF] Update on the mechanisms of action of anti-TNF-α antibodies and their clinical implications in inflammatory bowel disease

P Eder, K Linke, J Witowski - Pol Arch Med Wewn, 2016 - researchgate.net
… necrosis factor α (anti-TNF-α) antibodies in the therapy of inflammatory bowel disease (IBD)
are not completely understood. Binding of antibodies to transmembrane TNF-α seems to be …

… in the NF kB, TNFalpha, IL‐1beta, and IL‐18 pathways are associated with response to anti‐TNF therapy in Danish patients with inflammatory bowel disease

…, M Thomassen, A Green, A Bo Bojesen… - Alimentary …, 2019 - Wiley Online Library
… Anti-tumor necrosis factor-α (TNF-α) is used for the treatment of severe cases of IBD, including
Crohn's disease (CD) and ulcerative colitis (UC). However, one-third of the patients do not …