… understanding of the pathophysiology of TBI, the underlying mechanisms still need to be …
pathophysiological mechanism of TBI and various biochemical pathways involved in brain injury…

… pathophysiology of TBI, the underlying mechanisms are yet to be fully elucidated. While initial
brain … to the parenchyma, the ensuing secondary brain injuries often progress slowly over …

… As well as the burden to the individual, brain injuries also have an annual economic burden
of more than US$60 billion, due to both direct and indirect costs, such as loss of productivity. …

… a unique footprint of pathophysiologic change. Although … injury involve combinations of
focal and diffuse injury, this categorization does help frame key concepts regarding brain injury…

… Abstract: Background: Traumatic brain injury (TBI) constitutes … In severe traumatic brain
injury sufferers, a considerable … brain injury sufferers to an elevated degree of performing. …

… This delayed nature of the secondary injury suggests a potential therapeutic window. The
focus of this article is on the (1) pathophysiology of TBI and (2) potential therapies that include …

… brain injury mechanisms makes it difficult to simply and clearly differentiate between the
factors in patients with TBI [7, 8]. The central mechanisms of dysregulation after brain injury may …

… emission tomography ( 15 O PET) and brain tissue oximetry have demonstrated increased
oxygen diffusion gradients in hypoxic regions after traumatic brain injury (TBI). These data are …

Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality, affecting
millions annually worldwide. Although the majority of TBI patients return to premorbid …

… This review focuses on the mechanisms involved in traumatic brain injury, separating them
… mechanisms have been isolated in the hours to days following a traumatic brain injury that …