[HTML][HTML] Quality by Design-Guided Systematic Development and Optimization of Mucoadhesive Buccal Films

AAA Hassan, K Kristó, YHEY Ibrahim, G Regdon Jr… - Pharmaceutics, 2023 - mdpi.com
… chitosan-based mucoadhesive buccal films by relying on quality-by-design (QbD) principles.
… mucoadhesive buccal film based on CH was efficiently facilitated by the rational application

Drug delivery techniques for buccal route: formulation strategies and recent advances in dosage form design

S Barua, H Kim, K Jo, CW Seo, TJ Park, KB Lee… - Journal of …, 2016 - Springer
… be achieved, buccal drug … buccal dosage forms, anatomy of buccal mucosa, drug transport
mechanisms, and formulation strategies to enhance the drug permeation through the buccal

Development and Characterization of Buccal Film of Candesartan.

DR Malpure, SL Deore - Pharmaceutical Methods, 2016 - search.ebscohost.com
… A response surface methodology experimental design was applied for the optimization of
buccal film using Box-Behnken experimental design as it requires few runs with three or four …

[HTML][HTML] Applying design of experiments (DoE) on the properties of buccal film for nicotine delivery

J Suksaeree, B Chaichawawut, M Srichan… - e-Polymers, 2021 - degruyter.com
Design of experiments is used to optimize ratios between deproteinized natural rubber latex,
Eudragit ® NM 30 D, and pectin for nicotine buccal film with … The buccal film showed high …

… of composition on mechanical and physicochemical properties of mucoadhesive buccal films containing buprenorphine hydrochloride: From design of experiments to …

Z Kazemi, SM Taghizadeh, ST Keshavarz… - Journal of Drug Delivery …, 2020 - Elsevier
… In this study, mucoadhesive buccal films containing Buprenorphine Hydrochloride were
made. The parameters include polymers and plasticizers such as hydroxy propyl methyl …

3D printed bilayer mucoadhesive buccal film of estradiol: Impact of design on film properties, release kinetics and predicted in vivo performance

S Abdella, F Afinjuomo, Y Song, R Upton… - International Journal of …, 2022 - Elsevier
… 3D printing technology to design and develop bi-layered estradiol film with different infill …
at 1 mm/s and the maximum force applied to completely detach the formulated film from the …

An overview of polymeric dosage forms in buccal drug delivery: State of art, design of formulations and their in vivo performance evaluation

B Fonseca-Santos, M Chorilli - Materials Science and Engineering: C, 2018 - Elsevier
… This review summarizes the applications of polymers for designing of dosage forms for buccal
applied three times a day for 10 days. The results showed the application of buccal films

Design and evaluation of agarose based buccal films containing zolmitriptan succinate: Application of physical and chemical enhancement approaches

U Jillani, J Mudassir, MS Arshad, P Mehta… - Journal of drug delivery …, 2022 - Elsevier
… The ex-vivo mucoadhesion time was measured by applying mucoadhesive buccal films on
excised goat buccal mucosa. The bovine buccal mucosa was excised from the mouth cavity …

[HTML][HTML] Design and In Vitro/In Vivo Evaluation of Ultra-Thin Mucoadhesive Buccal Film Containing Fluticasone Propionate

HO Ammar, MM Ghorab, AA Mahmoud, HI Shahin - Aaps Pharmscitech, 2017 - Springer
… for local buccal delivery. The aim of the present study was to design mucoadhesive buccal
film … A light force was applied to fix the film on the membrane. The beaker was placed on a …

Design and evaluation of buccal films as paediatric dosage form for transmucosal delivery of ondansetron

R Trastullo, A Abruzzo, B Saladini, MC Gallucci… - European Journal of …, 2016 - Elsevier
… In particular, we are applying a second film layer onto a first one to achieve unidirectional
release towards the oral mucosa, avoiding drug release in the oral cavity and covering the …