Neuroprotective effect of gastrodin in methamphetamine-induced apoptosis through regulating cAMP/PKA/CREB pathway in cortical neuron

CL Ma, L Li, GM Yang, ZB Zhang… - Human & …, 2020 - journals.sagepub.com
… action of gastrodin might be related to the regulation of neurotrophic factors in neurons.
Gastrodin only reduced the apoptotic neurons but also protected the neurons by regulating the …

Atorvastatin inhibits neuronal apoptosis via activating cAMP/PKA/p‐CREB/BDNF pathway in hypoxic‐ischemic neonatal rats

L Yu, S Liu, R Zhou, H Sun, X Su, Q Liu, S Li… - The FASEB …, 2022 - Wiley Online Library
… effects and related mechanisms of atorvastatin on the regulation of neuronal apoptosis after
… Atorvastatin protects against cerebral ischemia/reperfusion injury through anti- inflammatory …

Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofol‑induced neurotoxicity in the hippocampus of neonatal rats

R Guan, J Lv, F Xiao, Y Tu… - Molecular Medicine …, 2019 - spandidos-publications.com
Neuronal cell apoptosis is associated with minor behavioural changes and cognitive dysfunction
in adolescent rats (24). When an apoptosis signal … exhibits a neuronal protective effect …

Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation‐Mediated Mfn1/2 Oligomerization

WK Ju, MS Shim, KY Kim, TL Park… - Oxidative Medicine …, 2019 - Wiley Online Library
… dynamics or function is associated with human ONH astrocytes from patients with POAG and
… of Mfn2 protects neuronal cells in the brain against hypoxia-induced apoptosis or ischemia/…

[HTML][HTML] … of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway

TJ Liu, JC Zhang, XZ Gao, ZB Tan, JJ Wang… - The Kaohsiung Journal …, 2018 - Elsevier
… Anesthesia by means of sevoflurane has been linked with … Note: cAMP protein was
expressed in cytoplasm and cell … Other study also indicated that sevoflurane protects against

Rolipram stimulates angiogenesis and attenuates neuronal apoptosis through the cAMP/cAMP‑responsive element binding protein pathway following ischemic stroke …

S Hu, Q Cao, P Xu, W Ji… - Experimental and …, 2016 - spandidos-publications.com
signaling cascades, including the cAMP-protein kinase A (… This study focused on the
protective effect of rolipram on … 1 and Bcl-2/Bcl-2-associated × protein, which are involved in the …

[HTML][HTML] A role for cAMP and protein kinase A in experimental necrotizing enterocolitis

BP Blackwood, DR Wood, C Yuan, J Nicolas… - The American Journal of …, 2017 - Elsevier
… activation are associated with increased apoptosis in NEC … been associated with survival
pathway activation in neuronal … PKA inhibition appears to protect against gut injury in our rat …

Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes

MS Shim, KY Kim, JH Bu, HS Nam, SW Jeong… - Cell death & …, 2018 - nature.com
… (cAMP) signaling pathway is associated with astrocyte … here that the cAMP/protein kinase
A (PKA) pathway is critical … of the PKA pathway also protected ONH astrocytes against

… , epigallocatechin-3-gallate, against sevoflurane-induced neuronal apoptosis involve regulation of CREB/BDNF/TrkB and PI3K/Akt/mTOR signalling pathways in …

M Ding, H Ma, Y Man, H Lv - Canadian journal of physiology …, 2017 - cdnsciencepub.com
signal transduction pathways is cyclic AMP response element-binding protein (CREB).
Phosphorylation at serine 133 by either cAMP/protein kinase … events related to the anti-apoptotic

Therapeutic implications of phosphorylation-and dephosphorylation-dependent factors of cAMP-response element-binding protein (CREB) in neurodegeneration

N Khakha, H Khan, A Kaur, TG Singh - Pharmacological Reports, 2023 - Springer
… nuclear factor erythroid 2-related factor 2 (Nrf2) pathway [26]. … cAMP/protein kinase pathway.
Endothelial cells and pericytes are both protected against collagenase-induced cell death, …