… Cellular view of the polysaccharide capsule formed by a complex lattice-work of interconnected
polymers that decreases in density, porosity and stiffness as it extends radially outward …

… The ability of the pathogenic fungus Cryptococcus neoformans to cause life-threatening …
of a capsule consisting of polysaccharide fibers. The size of the cell-associated capsule is …

… S1), further supporting that CAP genes are required for capsule formation under all
capsule-inducing conditions (11). Notably, the expression levels of CAP genes most robustly …

… The polysaccharide capsule of fungal pathogen Cryptococcus neoformans is a critical …
Cryptococcal polysaccharides are known to either remain attached to the cell as capsular …

… neoformans is required for infection and dissemination in the host. Our results indicate that
the capsule has a significant effect on reducing cryptococcal … It is formed by a porous matrix of …

… capsule of Cryptococcus neoformans is the primary virulence factor and one of the most
commonly studied aspects of this pathogenic yeast. Capsule … the capsule is of great interest to C. …

… capsule growth using specific inhibitors of the electron respiratory chain. We observed that
capsule … Our results confirm that capsule growth depends on mitochondrial activity, and open …

… They identified several genes required for capsule formation by complementing acapsular
… [16] and validated capsule as an essential virulence factor in C. neoformans. These seminal …

… neoformans capsule and biofilm formation. Interestingly, we found that this concentration of
lithium significantly reduced capsule formation by C. neoformans wild-type cells compared to …

… for an influence on capsule formation and found that although cell growth and capsule
formation were inhibited, the cells eventually recovered their ability to make capsule (Fig. 4D). …