Mutation signature analysis identifies increased mutation caused by tobacco smoke associated DNA adducts in larynx squamous cell carcinoma compared with oral …
AP South, NY den Breems, T Richa, U Nwagu… - Scientific reports, 2019 - nature.com
… We identify that mutations linked to DNA adducts associated with tobacco smoke exposure
are … growth and increased susceptibility to mutations from tobacco carcinogen DNA adducts. …
are … growth and increased susceptibility to mutations from tobacco carcinogen DNA adducts. …
Diet-related DNA adduct formation in relation to carcinogenesis
LY Hemeryck, L Vanhaecke - Nutrition reviews, 2016 - academic.oup.com
… Alcohol or ethanol consumption is a proven cause of cancer and has long been linked to
the occurrence of hepatocellular carcinomas and squamous-cell carcinomas of the oral cavity, …
the occurrence of hepatocellular carcinomas and squamous-cell carcinomas of the oral cavity, …
DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans
B Hwa Yun, J Guo, M Bellamri… - Mass spectrometry …, 2020 - Wiley Online Library
… It is now possible to measure some DNA adducts in human … formation and biological effects
of DNA adducts, and highlight our advances … for carcinogen DNA adduct biomarker research. …
of DNA adducts, and highlight our advances … for carcinogen DNA adduct biomarker research. …
DNA Adducts as Biomarkers To Predict, Prevent, and Diagnose Disease—Application of Analytical Chemistry to Clinical Investigations
C Hernandez-Castillo, J Termini… - Chemical Research in …, 2019 - ACS Publications
… , formation, and metabolism of DNA adducts has been one of … analytical methods to
measure DNA adducts, define their … cell carcinoma (ESCC) and head and neck squamous cell …
measure DNA adducts, define their … cell carcinoma (ESCC) and head and neck squamous cell …
Recent studies on DNA adducts resulting from human exposure to tobacco smoke
B Ma, I Stepanov, SS Hecht - Toxics, 2019 - mdpi.com
… We then applied this method to the analysis of HPB-releasing DNA adducts in oral cells …
cell carcinoma (HNSCC) patients and 35 cancer-free controls. HPB-releasing DNA adducts …
cell carcinoma (HNSCC) patients and 35 cancer-free controls. HPB-releasing DNA adducts …
Mass spectrometric profiling of DNA adducts in the human stomach associated with damage from environmental factors
I Ohnishi, Y Iwashita, Y Matsushita, S Ohtsuka… - Genes and …, 2021 - Springer
… for these carcinogenic and irreversible mutations involve DNA adduct formation, which is the
… to DNA and form DNA adducts. Certain DNA adducts may impede accurate DNA replication …
… to DNA and form DNA adducts. Certain DNA adducts may impede accurate DNA replication …
Toxicology of DNA adducts formed upon human exposure to carcinogens: Insights gained from molecular modeling
KA Wilson, RW Kung, SD Wetmore - Advances in Molecular Toxicology, 2016 - Elsevier
… The present contribution highlights the critical role of computer modeling in the DNA adduct
… DNA adducts will be provided. Subsequently, the structural information obtained from DNA …
… DNA adducts will be provided. Subsequently, the structural information obtained from DNA …
Tobacco-specific carcinogens induce hypermethylation, DNA adducts, and DNA damage in bladder cancer
… in levels of methylated metabolites, DNA adducts, and extensive DNA damage in bladder
cancer cells. Cotreatment of bladder cancer cells with these carcinogens and the methylation …
cancer cells. Cotreatment of bladder cancer cells with these carcinogens and the methylation …
DNA adducts from anticancer drugs as candidate predictive markers for precision medicine
A Stornetta, M Zimmermann, GD Cimino… - Chemical research in …, 2017 - ACS Publications
… DNA modification and biological response are addressed. A positive correlation between
DNA adduct … the high potential of using DNA adducts from anticancer drugs as mechanism-…
DNA adduct … the high potential of using DNA adducts from anticancer drugs as mechanism-…
Spatial mapping of the DNA adducts in cancer
KL Krieger, EK Mann, KJ Lee, E Bolterstein… - DNA repair, 2023 - Elsevier
… in DNA adduct detection and quantification methods, there is an opportunity to identify DNA
adducts … However, most DNA adduct detection methods require isolation or separation of the …
adducts … However, most DNA adduct detection methods require isolation or separation of the …
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