Therapeutic development of group B Streptococcus meningitis by targeting a host cell signaling network involving EGFR
… host cell signaling network comprised of S1P 2 , EGFR, and CysLT1. GBS exploitation of such
network … and knockdown cells, and gene knockout animals, as well as interrogation of the …
network … and knockdown cells, and gene knockout animals, as well as interrogation of the …
Protein self-assembly: a new frontier in cell signaling
… diverse roles that protein disorder plays in biology, multiple properties of prion self-assembly
provide appealing advantages in the context of signal processing and cellular ‘memory.’ …
provide appealing advantages in the context of signal processing and cellular ‘memory.’ …
Extracting intercellular signaling network of cancer tissues using ligand-receptor expression patterns from whole-tumor and single-cell transcriptomes
JX Zhou, R Taramelli, E Pedrini, T Knijnenburg… - Scientific Reports, 2017 - nature.com
… Given the wide functional variety of cells among tumor cells of the same clone (intraclonal
or … intra-tumor cell-cell signaling consists of heterotypic interactions between cells of distinct …
or … intra-tumor cell-cell signaling consists of heterotypic interactions between cells of distinct …
Surface sensing and signaling networks in plant pathogenic fungi
Y Kou, NI Naqvi - Seminars in Cell & Developmental Biology, 2016 - Elsevier
… require intricate coordination in cell signaling and differentiation in phytopathogenic fungi.
Here, we present an overview of our current understanding of cell signaling and infection-…
Here, we present an overview of our current understanding of cell signaling and infection-…
Information-theoretic analysis of multivariate single-cell signaling responses
T Jetka, K Nienałtowski, T Winarski… - PLoS computational …, 2019 - journals.plos.org
… The above questions resulted in a considerable interest to study cellular signaling within
the framework of information theory. Unfortunately, the utilization of the information-theoretic …
the framework of information theory. Unfortunately, the utilization of the information-theoretic …
Cell signaling pathways that promote radioresistance of cancer cells
MM Ouellette, S Zhou, Y Yan - Diagnostics, 2022 - mdpi.com
… (IR) can activate numerous cellular signaling pathways which lead to the induction of
senescence, apoptosis, autophagy (leading to cell death or survival), and/or cell cycle checkpoint …
senescence, apoptosis, autophagy (leading to cell death or survival), and/or cell cycle checkpoint …
SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks
… networks we made a leading step in signaling network research. However, with the
emergence of single-cell … a way to create cell-type specific networks with further developments. …
emergence of single-cell … a way to create cell-type specific networks with further developments. …
Dietary polyphenols suppress chronic inflammation by modulation of multiple inflammation-associated cell signaling pathways
… inflammation-associated cell signaling networks are deliberated. … inflammation-associated
cell signaling pathways, namely … various components of the networks. The suppressive effects …
cell signaling pathways, namely … various components of the networks. The suppressive effects …
High-content imaging platform for profiling intracellular signaling network activity in living cells
… Essential characteristics of cellular signaling networks include a complex interconnected
architecture and temporal dynamics of protein activity. The latter can be monitored by Förster …
architecture and temporal dynamics of protein activity. The latter can be monitored by Förster …
Initiation of T cell signaling by CD45 segregation at'close contacts'
… the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how
such segregation occurs and whether it can initiate signaling is unclear. Using structural and …
such segregation occurs and whether it can initiate signaling is unclear. Using structural and …