… moderate to severe injuries, traumatic brain injury is associated with a number of chronic
neurological and neuropsychiatric sequelae including neurodegenerative diseases such as …

Traumatic brain injury (TBI) is the paradigmatic example of acute brain injury, defined as
sudden and unexpected structural and/or functional damage to the brain. In western countries, …

… of brain injury, and neuroimaging and pathological investigations in the past decade
have enabled better characterisation of late neurodegenerative features associated with TBI. …

… we describe the dynamic interactions between acute response to injury and chronic processes
that may be involved in TBI-related pathogenesis and progression of neurodegeneration. …

… injury processes including persistent neuroinflammation evolve over time and can contribute
to chronic … -associated neuroinflammation and chronic neurodegeneration. We examined …

… links between TBI and chronic neurodegeneration. … the later onset of progressive
neurodegenerative disease has ignited … TBI in contributing to chronic neurodegenerative …

… disorders such as Alzheimer disease (AD), chronic traumatic encephalopathy (CTE…
neurodegenerative diseases. This review encompasses acute effects and chronic …

… Acute neuropathologies and chronic neurodegeneration (A) Healthy, myelinated axon prior
to traumatic brain injury (TBI). The box shows detail of the mid-segment of axon with central …

… risk for the development of chronic neurodegenerative diseases, notably chronic traumatic …
neurodegenerative diseases can exacerbate the severity and prognosis of acute brain injuries…

… traumatic brain injuries. Formerly known as an acute injury, chronic neurodegenerative
symptoms … have caused the scientific community to consider chronic aspects of the disorder. The …