Ischemia-reperfusion injury in marginal liver grafts and the role of hypothermic machine perfusion: molecular mechanisms and clinical implications

Z Czigany, I Lurje, M Schmelzle, W Schöning… - Journal of Clinical …, 2020 - mdpi.com
… The clinical effects of IRI can manifest as a broad spectrum of short-term and long-term
complications, resulting in an overall inferior patient survival [5,6]. IRI-induced complications …

[HTML][HTML] Feasibility of using marginal liver grafts in living donor liver transplantation

X Lan, H Zhang, HY Li, KF Chen, F Liu… - World journal of …, 2018 - ncbi.nlm.nih.gov
… In this review, we define marginal liver grafts for LDLT as small-for-size grafts, older donors,
moderate or severe steatosis of liver grafts, chronic hepatitis, and grafts with tumors. The …

Expanding the margins: high volume utilization of marginal liver grafts among> 2000 liver transplants at a single institution

KJ Halazun, RC Quillin, R Rosenblatt, A Bongu… - Annals of …, 2017 - journals.lww.com
… Unadjusted patient survival for 2050 patient transplanted at NYP by graft type showing
no significant difference between marginal liver grafts (ML grafts) and standard liver grafts (SL …

[HTML][HTML] Ischemia-free liver transplantation improves the prognosis of recipients using functionally marginal liver grafts

S Wang, X Lin, Y Tang, Y Liang, M Zhang… - Clinical and …, 2024 - ncbi.nlm.nih.gov
… This study aimed to clarify the poor outcomes of functionally marginal liver grafts (FMLs) and
provide evidence for the improvement of ischemia-free liver transplantation (IFLT) after FML …

[HTML][HTML] Extended criteria donors in liver transplantation—from marginality to mainstream

A Nair, K Hashimoto - Hepatobiliary Surgery and Nutrition, 2018 - ncbi.nlm.nih.gov
New York group in a new report note that elderly grafts (> 70 years age) formed only 4.3%
of all 71,926 liver transplants done in the MELD era within UNOS, thus representing an …

Multinational analysis of marginal liver grafts based on the Eurotransplant extended donor criteria

S Moosburner, MS Patel, BK Wang, J Prasadh… - Annals of …, 2024 - journals.lww.com
… This study evaluates the outcome of over 70,000 transplants, analyzing the impact of marginal
liver grafts based on the “Eurotransplant Extended Donor Criteria”, comparing a German …

Assessment of trends in transplantation of liver grafts from older donors and outcomes in recipients of liver grafts from older donors, 2003-2016

CE Haugen, CM Holscher, X Luo, MG Bowring… - JAMA …, 2019 - jamanetwork.com
Importance In light of the growing population of older adults in the United States, older donors
(aged ≥70 years) represent an expansion of the donor pool; however, their organs are …

[PDF][PDF] Prognostic Factors in Liver Transplant with Marginal Grafts-Review of the Literature

M Serban, I Balescu, S Petrea, B Gaspar… - Chirurgia (Bucharest …, 2024 - revistachirurgia.ro
… Goldaracena et al. concluded that extremely marginal liver grafts (with a score ≥ 3 ) could
… Extremely marginal liver grafts from deceased donors have outcome similar to ideal grafts. …

[HTML][HTML] A marginal liver graft with hyperbilirubinemia transplanted successfully by ischemia-free liver transplantation

C Huang, Z Chen, T Wang, X He… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
The shortage of transplant organs remains a serious issue worldwide, and using liver grafts
from extended criteria donors could expand the donor pool. Extended criteria donor liver …

Steatosis in liver transplantation: current limitations and future strategies

I Linares, M Hamar, N Selzner, M Selzner - Transplantation, 2019 - journals.lww.com
… persufflation has already moved into the clinical application. The first human trial was
reported in 2008, where VSOP was applied to rescue marginal liver grafts with less than 20% …