RNA-seq analysis of microglia reveals time-dependent activation of specific genetic programs following spinal cord injury

HN Noristani, YN Gerber, JC Sabourin… - Frontiers in molecular …, 2017 - frontiersin.org
… competence to regrow following injury, although not spontaneously. Spinal cord injury (SCI) …
using RNA-sequencing. We demonstrate that activation of microglia is time-dependent post-…

Transcriptome profile of rat genes in injured spinal cord at different stages by RNA-sequencing

LL Shi, N Zhang, XM Xie, YJ Chen, R Wang, L Shen… - BMC genomics, 2017 - Springer
… Although the genes associated with damage and repair of spinal cord injury are still largely
unknown, the RNA-Seq analysis presented in this study will expand our understanding of the …

Analyses of gene expression profiles in the rat dorsal horn of the spinal cord using RNA sequencing in chronic constriction injury rats

H Du, J Shi, M Wang, S An, X Guo, Z Wang - Journal of neuroinflammation, 2018 - Springer
… Using the Illumina HiSeq 4000 platform, we examined differentially expressed genes (DEGs)
in the rat dorsal horn by RNA sequencing (RNA-seq) between CCI and control groups. …

Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury

H Wei, X Wu, J Withrow, RCD Duran, S Singh… - Cell reports, 2023 - cell.com
… spinal cord after injury and contribute to regeneration remains elusive. We perform single-cell
RNA sequencing of GFAP-expressing cells from sub-chronic spinal cord injury models and …

Expression of long non-coding RNAs in complete transection spinal cord injury: a transcriptomic analysis

L Ding, WJ Fu, HY Di, XM Zhang, YT Lei… - Neural Regeneration …, 2020 - journals.lww.com
cord injury (SCI), the expression signatures of lncRNAs were profiled using RNA sequencing
(RNA-seq) … A subset of these RNA-seq results was validated by quantitative real-time PCR. …

Single‐cell RNA sequencing for traumatic spinal cord injury

Y Cao, S Zhu, B Yu, C Yao - The FASEB Journal, 2022 - Wiley Online Library
… Single- cell RNA sequencing (scRNA- seq) has provided … the diversity of spinal cord
cell types. Specifically, scRNA- … in injured spinal cord at different stages by RNAsequencing. …

Single-cell RNA sequencing reveals Nestin+ active neural stem cells outside the central canal after spinal cord injury

M Shu, X Xue, H Nie, X Wu, M Sun, L Qiao, X Li… - Science China Life …, 2022 - Springer
cord hold great potential for repair after spinal cord injury (… the NSCs source in the spinal
cord. However, the ependyma … SCI by single-cell RNA-sequencing (scRNA-seq). We identified …

Screening the immune-related circRNAs and genes in mice of spinal cord injury by RNA sequencing

Y Li, B Wang, W Sun, C Kong, G Li, X Chen… - Frontiers in …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a pathological condition that leading to serious nerve damage,
disability and even death. Increasing evidence have revealed that circular RNAs (circRNAs) …

Transcriptome Profiling after Early Spinal Cord Injury in the Axolotl and Its Comparison with Rodent Animal Models through RNA-Seq Data Analysis

JC González-Orozco, I Escobedo-Avila, I Velasco - Genes, 2023 - mdpi.com
… By analyzing RNA-seq data … cords in axolotls and rodents after traumatic injury, to determine
the gene expression differences between these species during the first days post-injury (dpi)…

RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation

KE Stephens, Z Chen, E Sivanesan, SN Raja… - Molecular …, 2018 - journals.sagepub.com
… To determine the effects of SCS on gene expression in the spinal cord that is ipsilateral to
the side of nerve injury, we compared RNA-seq data obtained 39 days following CCI to that of …