Cytochrome P450 expression and regulation in the brain
W Kuban, WA Daniel - Drug Metabolism Reviews, 2021 - Taylor & Francis
… liver, which also exhibits the highest expression and concentration of transmembrane cytochrome
P450 … Total CYP protein content in the brain is significantly lower compared to the liver …
P450 … Total CYP protein content in the brain is significantly lower compared to the liver …
The regulation of liver cytochrome P450 expression and activity by the brain serotonergic system in different experimental models
E Bromek, WA Daniel - Expert Opinion on Drug Metabolism & …, 2021 - Taylor & Francis
… Cytochrome P450 (CYP) enzymes are members of the … The expression of liver cytochrome
P450 is under the … -pituitary-liver axis (HPL) affecting growth hormone level/action in the …
P450 is under the … -pituitary-liver axis (HPL) affecting growth hormone level/action in the …
Physiological content and intrinsic activities of 10 cytochrome P450 isoforms in human normal liver microsomes
HF Zhang, HH Wang, N Gao, JY Wei, X Tian… - … of Pharmacology and …, 2016 - ASPET
… In conclusion, we first offered the physiologic data of 10 P450 isoform contents and found …
P450 expression in human normal livers. The effects of gene polymorphisms on intrinsic P450 …
P450 expression in human normal livers. The effects of gene polymorphisms on intrinsic P450 …
Expression of cytochrome P450 isozyme transcripts and activities in human livers
J Liu, YF Lu, JC Corton, CD Klaassen - Xenobiotica, 2021 - Taylor & Francis
… intact liver … liver samples to profile the constitutive expression of CYP1A2, 2B6, 2C8, 2C9,
2C19, 2D6, 2E1, 3A4, and 4A11 enzyme activity and transcript levels. The mRNA expression of …
2C19, 2D6, 2E1, 3A4, and 4A11 enzyme activity and transcript levels. The mRNA expression of …
Hepatic cytochrome P450 activity, abundance, and expression throughout human development
… Herein, we have sought to expand our knowledge of P450 expression and activity in the
human liver from early gestation to late adulthood using classic techniques to measure gene …
human liver from early gestation to late adulthood using classic techniques to measure gene …
[PDF][PDF] The role of human cytochrome P450 2E1 in liver inflammation and fibrosis
… Here, we analyzed mice expressing only the human CYP2E1 gene (hCYP2E1) to … function
with different liver injuries. After intragastric alcohol feeding, CYP2E1 expression was induced …
with different liver injuries. After intragastric alcohol feeding, CYP2E1 expression was induced …
Differences in cytochrome p450 enzyme expression and activity in fetal and adult tissues
… To evaluate global transcriptomic differences in CYP expression between adult liver and
fetal liver and/or placenta, we searched two public databases, National Center for …
fetal liver and/or placenta, we searched two public databases, National Center for …
Sexual dimorphism in the expression of cytochrome P450 enzymes in rat heart, liver, kidney, lung, brain, and small intestine
SH Gerges, AOS El-Kadi - Drug Metabolism and Disposition, 2023 - ASPET
… Elucidating sex-specific differences in P450 enzyme levels could help … expression levels
of different cytochrome P450 (P450) enzymes between male and female rats in the heart, liver, …
of different cytochrome P450 (P450) enzymes between male and female rats in the heart, liver, …
Diet-induced non-alcoholic fatty liver disease affects expression of major cytochrome P450 genes in a mouse model
T Chiba, K Noji, S Shinozaki, S Suzuki… - Journal of Pharmacy …, 2016 - academic.oup.com
… Non-alcoholic fatty liver disease (NAFLD) is associated with impaired liver function, and …
expression of major cytochrome P450 (CYP) subtypes in the liver and whether the expression …
expression of major cytochrome P450 (CYP) subtypes in the liver and whether the expression …
Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver
… In consideration of the changes of expression and activities of P450s in mouse liver during
… P450 expression is in an age-dependent manner. The current study determined expression …
… P450 expression is in an age-dependent manner. The current study determined expression …
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