Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
… The actions of pro-atherogenic cytokines can be better appreciated based on experimental
studies with hyperlipidaemic mouse models. For example, TNF-α −/− , apolipoprotein E (ApoE…

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Taylor & Francis
… of atherosclerotic mouse models have greatly improved our understanding of the role of
cytokines and … Normally wild-type mice do not develop atherosclerosis, however, ApoE knockout …

Both gut microbiota and cytokines act to atherosclerosis in ApoE−/− mice

Q Liu, Y Li, X Song, J Wang, Z He, J Zhu, H Chen… - Microbial …, 2020 - Elsevier
… the microbiota and cytokines changed together in the process of mice with atherosclerosis.
… mechanisms involved in the process of atherosclerosis. These results imply the dysbiosis …

The impact of cytokines in coronary atherosclerotic plaque: current therapeutic approaches

P Tsioufis, P Theofilis, K Tsioufis… - International Journal of …, 2022 - mdpi.com
… established the role of inflammatory cytokines in coronary artery disease, … cytokine-targeted
treatment approaches have emerged as potential tools in the management of atherosclerotic

Targeted delivery of anti-inflammatory cytokine by nanocarrier reduces atherosclerosis in Apo E−/-mice

M Kim, A Sahu, Y Hwang, GB Kim, GH Nam, IS Kim… - Biomaterials, 2020 - Elsevier
… the cytokine in the atherosclerosis lesions. IL10 delivered by NC was bioactive and reduced
the production of pro-inflammatory cytokinecytokine delivery for preventing atherosclerotic

[HTML][HTML] Inflammation in atherosclerosis

S Taleb - Archives of cardiovascular diseases, 2016 - Elsevier
… The majority of T cells in mouse and human atherosclerotic plaques … cytokines, CD4+ T
lymphocytes differentiate into a Th1, Th2 or Th17 lineage. Besides producing specific cytokines

Act locally, act globally—microbiota, barriers, and cytokines in atherosclerosis

N Kurilenko, AR Fatkhullina, A Mazitova, EK Koltsova - Cells, 2021 - mdpi.com
… Genetic or pharmacological studies in micecytokines have been shown to regulate
atherosclerosis [2], here we focus on cytokines which have an established role in atherosclerosis

Anti-cytokine therapy for prevention of atherosclerosis

TV Kirichenko, IA Sobenin, D Nikolic, M Rizzo… - Phytomedicine, 2016 - Elsevier
… of inflammatory cytokines in the development of atherosclerotic … It is shown in studies in
various animal models of atherosclerosis … in atherosclerotic lesions in ApoE-deficient mice with …

Anti-inflammatory therapy for atherosclerosis: focusing on cytokines

AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
cytokine and appears in atherosclerotic lesions triggered by multiple modified LDL [48]. In the
ApoE–/– mouse … in ApoE–/– mice resulted in significant 60% atherosclerosis lowering. It is …

Role of inflammatory cytokines in genesis and treatment of atherosclerosis

E Biros, JE Reznik, CS Moran - Trends in cardiovascular medicine, 2022 - Elsevier
… , a primary inflammatory cytokine in progressive atherosclerosis, … Here, we discuss the
pro-atherosclerotic implication of this … an example where treatment of pregnant mice with 1-methyl-…