Functional role of B cells in atherosclerosis

SD Ma, M Mussbacher, EV Galkina - Cells, 2021 - mdpi.com
… the release of cytokines. All of these functions have the potential to affect atherosclerosis by
… the mechanism of B cell activation under atherosclerosis-prone conditions. By summarizing …

Multi-analyte profiling in human carotid atherosclerosis uncovers pro-inflammatory macrophage programming in plaques

J Shalhoub, LE Viiri, AJ Cross… - Thrombosis and …, 2016 - thieme-connect.com
… Importantly, this cytokine and chemokine signature of symptomatic compared to asymptomatic
carotid atherosclerosis complies largely with the cytokine and chemokine signature for M1 …

Macrophage: a key therapeutic target in atherosclerosis?

E Taghizadeh, F Taheri, PG Renani… - Current …, 2019 - ingentaconnect.com
… options to treat atherosclerosis. Targeting recruitment, polarization, cytokine profile extracellular
… as potential therapeutic approaches against atherosclerosis. Conclusion: Monocytes/…

Basic pathogenic mechanisms of atherosclerosis

HAH Alfarisi, ZBH Mohamed… - Egyptian Journal of Basic …, 2020 - Taylor & Francis
… through production of inflammatory cytokines. Understanding of pathogenic role of genetics,
epigenetics, inflammatory and immune mechanisms in atherosclerosis at molecular level …

Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity

NG Nikiforov, TV Kirichenko, MV Kubekina… - Cytokine, 2023 - Elsevier
… immune tolerance of monocytes in atherosclerosis, we aimed to evaluate the secretion of
cytokines and chemokines by cells obtained from individuals with subclinical atherosclerosis. …

Atherosclerosis and inflammation. New therapeutic approaches

J Pedro-Botet, E Climent, D Benaiges - Medicina Clínica (English Edition), 2020 - Elsevier
… the pathophysiological contribution of inflammation to atherosclerosis and the effect of lipid-…
anti-inflammatory cytokines and chemokines, have also been identified in atherosclerosis. …

Immunity in atherosclerosis: focusing on T and B cells

AV Poznyak, EE Bezsonov, TV Popkova… - International Journal of …, 2021 - mdpi.com
… of the key cytokines of the Th2 subset, IL-4, significantly suppresses Th1 differentiation and
follows IFN-γ secretion, which indicates a potential protective role against atherosclerosis. …

Monocyte subsets in atherosclerosis and modification with exercise in humans

NH Aw, E Canetti, K Suzuki, J Goh - Antioxidants, 2018 - mdpi.com
Atherosclerosis is a progressive … cytokine and chemokine production. Such modulation
could reflect a potential mechanism for the cardio-protective effect of exercise on atherosclerosis. …

Study of the NLRP3 inflammasome component genes and downstream cytokines in patients with type 2 diabetes mellitus with carotid atherosclerosis

J Lee, J Wan, L Lee, C Peng, H Xie, C Lee - Lipids in health and disease, 2017 - Springer
cytokine production in T2DM have been elucidated. Indeed, inflammatory cytokines are …
and downstream cytokine production is ambiguous. IL-1β and IL-18 are two multifunctional …

The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
… The role of IgA in atherosclerosis remains elusive. B cells also produce various cytokines
such as proatherogenic tumour necrosis factor (TNF) and antiatherogenic IL-10. cDC, …