Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6

DJ Tyrrell, DR Goldstein - Nature Reviews Cardiology, 2021 - nature.com
… -related atherosclerosis. We acknowledge that other inflammatory pathways and cytokines
could contribute to age-related atherosclerosis, and the source of these cytokines (including IL…

Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
… represents the transformation of inflammation in atherosclerosis from theory to practice. … in
the treatment of atherosclerosis, including inhibiting pro-inflammatory cytokines, blocking key …

Macrophages and their role in atherosclerosis: pathophysiology and transcriptome analysis

YV Bobryshev, EA Ivanova… - BioMed research …, 2016 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease triggered … by secreting proinflammatory
cytokines and chemokines and … play in the pathogenesis of atherosclerosis makes them an …

The changing landscape of atherosclerosis

P Libby - Nature, 2021 - nature.com
… When activated by proinflammatory cytokines or other irritative stimuli related to …
Chemoattractant cytokines can direct the migration of these bound leukocytes into the intima…

Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions

P Raggi, J Genest, JT Giles, KJ Rayner, G Dwivedi… - Atherosclerosis, 2018 - Elsevier
… clonal hematopoietic expansion and accelerate atherosclerosis in hyperlipidemic mice [34]. …
atherosclerosis in TET2-deficient animals demonstrated an increased secretion of cytokines

The Role of miRNA‐146a and Proinflammatory Cytokines in Carotid Atherosclerosis

P Huang, X He, M Xu - BioMed Research International, 2020 - Wiley Online Library
The aim of this study was to investigate the expression and significance of miRNA‐146a in
peripheral blood of patients with carotid atherosclerosis (CAS). Patients with CAS were …

Roles of cells from the arterial vessel wall in atherosclerosis

D Wang, Z Wang, L Zhang, Y Wang - Mediators of inflammation, 2017 - Wiley Online Library
… These cytokines are likely derived from other cells within lesion cells; thus, the concrete
functions of these cytokines in the progression of atherosclerosis remain unclear [35]. …

Cytokines and microRNA in coronary artery disease

H Mirzaei, GA Ferns, A Avan, MG Mobarhan - Advances in clinical …, 2017 - Elsevier
… studies on the role of cytokines in CVD, novel … cytokines involved in atherosclerotic CVD.
In addition, we have briefly referred to the miRNAs, which affect cytokines in atherosclerosis

Targeting inflammation in atherosclerosis—from experimental insights to the clinic

O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
… non-invasive therapeutic intervention for atherosclerosis focused primarily on … atherosclerosis
from conjecture to clinical reality 2 . This study targeted a specific pro-inflammatory cytokine

Immunobiology of atherosclerosis: a complex net of interactions

B Herrero-Fernandez, R Gomez-Bris… - International Journal of …, 2019 - mdpi.com
… , and atherosclerosis the principal factor underlying cardiovascular events. Atherosclerosis is
a … major innate and adaptive immune factors in atherosclerosis. Studies such as this are the …