The emerging role of Th1 cells in atherosclerosis and its implications for therapy

J Chen, X Xiang, L Nie, X Guo, F Zhang… - Frontiers in …, 2023 - frontiersin.org
… the onset and progression of atherosclerosis. Besides, Th1 … atherosclerosis and propose
novel preventative and therapeutic approaches targeting Th1 cell-associated specific cytokines

Interleukin-1 beta as a target for atherosclerosis therapy: biological basis of CANTOS and beyond

P Libby - Journal of the American College of Cardiology, 2017 - jacc.org
… Beyond the chronic phase of atherosclerosis in secondary prevention, inflammation
participates pivotally in other clinical scenarios. Cytokines modulate the healing of acute ischemic …

The role of interleukin-27 in atherosclerosis: A contemporary review

M Jafarizade, F Kahe, S Sharfaei, K Momenzadeh… - Cardiology, 2021 - karger.com
… in atherosclerosis has been attributed to the imbalance between pro-inflammatory Th1 and
anti-inflammatory Th2 cytokines as … of the IL12-related cytokines, plays an important role in all …

Targeting early atherosclerosis: a focus on oxidative stress and inflammation

P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
atherosclerosis by secreting autoantibodies and cytokines that … This is achieved by releasing
chemokines and cytokines that … , thus accelerating the development of atherosclerosis [46]. …

Adaptive immune responses in human atherosclerosis

S Lee, B Bartlett, G Dwivedi - International journal of molecular sciences, 2020 - mdpi.com
… In response to antigens, both T CM and T EM can produce effector cytokines, but T CM …
(T TE ) that proliferate poorly but have strong cytokine-producing and cytotoxic capabilities. …

Systemic inflammatory response and atherosclerosis: the paradigm of chronic inflammatory rheumatic diseases

A Arida, AD Protogerou, GD Kitas… - International journal of …, 2018 - mdpi.com
… of cytokines and atherosclerosis in AS and PsA is scarce. Among pro-inflammatory cytokines,
… As in RA, TNFa is implicated in the pathogenesis of atherosclerosis and may also have a …

Molecular and cellular mechanisms of inflammation in atherosclerosis

NM Popa-Fotea, CE Ferdoschi… - Frontiers in …, 2023 - frontiersin.org
… of atherosclerosis whose function is to stimulate the immune cells and the production of further
cytokines. This … Mast cells also contribute to atherosclerosis by secretion of cytokines and …

Dose-dependent association of inflammatory cytokines with carotid atherosclerosis in transient ischaemic attack: Implications for clinical trials

S Coveney, JJ McCabe, S Murphy, O Belton… - Cerebrovascular …, 2022 - karger.com
… We investigated the association of acute inflammatory cytokines and high-sensitivity C-reactive
protein (CRP) with recently symptomatic carotid atherosclerosis in a prospective cohort …

NLRP3 inflammasome and the IL-1 pathway in atherosclerosis

A Grebe, F Hoss, E Latz - Circulation research, 2018 - Am Heart Assoc
… Here, we review the mechanisms of NLRP3 inflammasome activation and proinflammatory
IL-1 family cytokine production in the context of atherosclerosis and discuss treatment …

Infections, atherosclerosis, and coronary heart disease

NVK Pothineni, S Subramany, K Kuriakose… - European heart …, 2017 - academic.oup.com
… endothelium as well as an indirect effect by systemic cytokine release, both of which contribute
to accelerated atherosclerosis. Infectious agents that have been linked to atherosclerotic …