… response required for the clearance of bacterial infection [44]. Although a large portion of
sepsis patients might die during the initial cytokine storm, patients who survive this stage could …

… In summary, while the innate immune system is rich in potential therapeutic targets and
remains a promising area of research, as has been demonstrated by the study of cytokines in this …

… Pro-inflammatory cytokines implicated in sepsis pathogenesis include tumour necrosis …
eliminating these cytokines confers protection in acute animal models of fulminant infection 10 . …

… , which is seen as the primary driver of sepsis pathogenesis. Throughout the onset and
progression of sepsis, the generation of cytokines not only facilitates the activation of coagulation …

MDSCs in sepsis-induced immunosuppression and its potential therapeutic targets - … The
release of anti-inflammatory cytokines such as IL-10 and TGF-β contributes to sepsis-induced …

… In summary, histone significantly contributed to the release of pro-inflammatory cytokines
and vascular endothelial injury in sepsis which unfortunately disrupt the fine balance and …

… overview of the mechanisms and potential therapeutic targets underlying pyroptosis in sepsis
identified in recent decades, looking forward to the future direction of treatment for sepsis. …

… As T-helper cell (Th)17 cytokines play a key role in driving mucosal immune responses,
this review focuses on the role of Th17 cytokines, interleukin (IL)-17 and IL-22 in the …

… sepsis, while enhancing M2 polarization might produce anti-inflammatory cytokines and
protect the body from sepsis … markers and potential therapeutic targets for patients with septic-…

… Adaptive immune cells also increase the expression of many overlapping and cell-specific
cytokines and metabolic pathways [Citation31]. Successful acute inflammation returns to …