[HTML][HTML] Intrauterine therapy of cytomegalovirus infection with valganciclovir: review of the literature

V Seidel, C Feiterna-Sperling, JP Siedentopf… - Medical microbiology …, 2017 - Springer
… asymptomatic CMV infection and consecutive fetal CMV infection confirmed by high CMV
VL in AF. Serologic findings in the first trimester hinted at a primary CMV infection. The first …

Lessons learned from a randomized study of oral valganciclovir versus parenteral ganciclovir treatment of cytomegalovirus disease in solid organ transplant recipients …

A Åsberg, A Humar, H Rollag… - Clinical Infectious …, 2016 - academic.oup.com
Treatment of CMV infection has been difficult in the past, requiring intravenous treatment
with … The development of ganciclovir's prodrug, valganciclovir, with 10-fold greater oral …

[HTML][HTML] Role of valganciclovir in children with congenital CMV infection: a review of the literature

D Pata, D Buonsenso, A Turriziani-Colonna, G Salerno… - Children, 2023 - mdpi.com
… for congenital CMV infections. Currently, two different antivirals are in use: oral valganciclovir
(VGC) and … The aim of our study was to analyze the available data on the VGC treatment of …

Efficacy, safety, and pharmacokinetics of oral valganciclovir in patients with congenital cytomegalovirus infection

E Suganuma, H Sakata, N Adachi, S Asanuma… - Journal of Infection and …, 2021 - Elsevier
cytomegalovirus infection at our hospital during the study period, 36 patients (47%) received
antiviral treatment. Of … Since one patient who had completed treatment with VGCV before …

Efficacy and safety according to the dose of valganciclovir for cytomegalovirus prophylaxis in transplantation: network meta-analysis using recent data

JH Lee, H Lee, SW Lee, SD Hwang, JH Song - Transplantation …, 2021 - Elsevier
… In conclusion, 450 mg of valganciclovir was effective in preventing CMV infection in kidney
transplant patients compared with the standard dose and showed the best rank probability. In …

[HTML][HTML] Congenital cytomegalovirus infection: update on diagnosis and treatment

G Chiopris, P Veronese, F Cusenza, M Procaccianti… - Microorganisms, 2020 - mdpi.com
… In the case of symptomatic cCMV, we actually recommend treatment with oral valganciclovir
Valganciclovir is reserved for congenitally-infected neonates with the symptomatic disease …

[HTML][HTML] Management of cytomegalovirus infection in pregnancy: is it time for valacyclovir?

L Zammarchi, T Lazzarotto, M Andreoni… - … and Infection, 2020 - Elsevier
… In conclusion, the valacyclovir treatment significantly increased the portion of asymptomatic
neonates from 43%, without treatment, to 82% with treatment. There was no overlap in 95% …

[HTML][HTML] In utero treatment of congenital cytomegalovirus infection with valacyclovir in a multicenter, open-label, phase II study

M Leruez-Ville, I Ghout, L Bussières… - American journal of …, 2016 - Elsevier
valacyclovir given in pregnancy is effective for improving the outcome of moderately
symptomatic infected … of an antiviral drug to treat cytomegalovirus-infected fetuses. Moreover, this …

[HTML][HTML] New developments in the management of cytomegalovirus infection after transplantation

A Meesing, RR Razonable - Drugs, 2018 - Springer
… and valganciclovir) serves as the first-line drug for CMV prevention and therapy, while
foscarnet and cidofovir are reserved for the management of refractory and resistant CMV infection. …

Advances in the development of therapeutics for cytomegalovirus infections

E Acosta, T Bowlin, J Brooks, L Chiang… - … Journal of Infectious …, 2020 - academic.oup.com
… Second, the treatment of congenital CMV infections with valganciclovir has beneficially
improved both hearing and neurologic outcomes, both fundamental advances for these children. …