Temporal transcriptomic and proteomic landscapes of deteriorating pancreatic islets in type 2 diabetic rats

J Hou, Z Li, W Zhong, Q Hao, L Lei, L Wang, D Zhao… - Diabetes, 2017 - Am Diabetes Assoc
… tag–based quantitative proteomics technology to measure … changes of pancreatic islets in
Goto-Kakizaki (GK) rats from 4 to … and proteome data offer a valuable resource for the diabetes

Liver proteome in diabetes type 1 rat model: Insulin-dependent and-independent changes

CP Braga, CHT Boone, RA Grove… - Omics: a journal of …, 2016 - liebertpub.com
… on the hepatic proteome, streptozotocin (STZ) was used to induce DM1 in a rat model. This
is a … Although STZ-induced proteomic studies have been published, the subset of proteins …

Proteomics of the rat myocardium during development of type 2 diabetes mellitus reveals progressive alterations in major metabolic pathways

AV Edhager, JA Povlsen, B Løfgren… - Journal of proteome …, 2018 - ACS Publications
… metabolic pathways in the Zucker diabetic fatty rat heart as T2DM develops using MS based
proteomics. The prediabetic state only induced minor pathway changes, whereas onset and …

[HTML][HTML] Proteome profiling in the aorta and kidney of type 1 diabetic rats

M Al Hariri, M Elmedawar, R Zhu, MA Jaffa, J Zhao… - PLoS …, 2017 - journals.plos.org
… In this study, we aimed at identifying the global protein changes in response to T1DM-induced
hyperglycemia in the aorta and kidney, by employing Liquid chromatography-tandem …

Proteomic study on the new potential mechanism and biomarkers of diabetes

N Wang, S Zhang, F Zhu, Y Yang… - PROTEOMICS …, 2019 - Wiley Online Library
… the retina of diabetic rats compared with normal rats, and five … with the proteomic results with
significant changes. Among … the STZ-induced type 2 diabetic mice compared with the control …

A proteomic approach to identify metalloproteins and metal-binding proteins in liver from diabetic rats

CP Braga, JCS Vieira, RA Grove, CHT Boone… - International journal of …, 2017 - Elsevier
… that the proteomic profile of the C group was closer to the proteomic … associations, particularly
related to diabetes and insulin treatment. … the interactions and changes in DM1 pathology. …

Effects of obesity and diabetes on sperm cell proteomics in rats

MG Carvalho, KM Silva, VHV Aristizabal… - Journal of Proteome …, 2021 - ACS Publications
… In fact, the changes in proteomics data in our … I diabetes, which may be justified by the
metabolic changes induced by obesity. (3) Despite the differences between type I and II diabetes, …

[HTML][HTML] Proteomics analysis of the spinal dorsal horn in diabetic painful neuropathy rats with electroacupuncture treatment

X Yu, X Chen, W Liu, M Jiang, Z Wang… - Frontiers in …, 2021 - frontiersin.org
… )-diabetic rat model can be used to mimic the symptoms and pathological changes that occur
… cord damage and atrophy in patients with diabetes, and peripheral nerve stimulation can …

Proteomic analysis of serum biomarkers for prediabetes using the Long‐Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus

E Takahashi, H Unoki‐Kubota… - Journal of Diabetes …, 2017 - Wiley Online Library
… proteins were differentially changed between LEA rats and BN rats at all three time-points
examined. Among the five proteins, SERPINA3N was increased significantly in the sera of LEA …

Comparative proteomic analysis of two differently extracted coptis chinensis in the treatment of type 2 diabetic rats

X Qiu, X Wei, H Guan, H Su, J Gong… - Evidence‐Based …, 2018 - Wiley Online Library
… In this study, a rat model of type 2 diabetes was established and treated with supercritical‐…
type 2 diabetic rats and CC‐treated rats using an iTRAQ‐based quantitative proteomic analysis…