Solubility and dissolution rate enhancement of ibuprofen by co-milling with polymeric excipients

A Hussain, G Smith, KA Khan, NI Bukhari… - European Journal of …, 2018 - Elsevier
… to enhance the solubility and dissolution rate of ibuprofen. … are the enhancement of solubility
and dissolution rate of … the effect on solubility and dissolution rate of ibuprofen determined. …

Dissolution rate enhancement and physicochemical characterization of carbamazepine-poloxamer solid dispersions

DP Medarević, K Kachrimanis, M Mitrić… - Pharmaceutical …, 2016 - Taylor & Francis
Enhanced dissolution rate of drug from SDs is ascribed to the combination of … dissolution
is much faster, and in the case of solid solutions it is determined by the carrier dissolution rate

Dissolution rate enhancement of repaglinide by solid dispersion

XD Yang, WS Li, YJ Tian, CG Liu, DH Gao… - Tropical Journal of …, 2016 - ajol.info
Dissolution studies were carried out in pH 7.4 phosphate … The solubility of pure repaglinide
was enhanced from 22.5±5.0 … solubility and dissolution rate of repaglinide are enhanced by …

Development and preliminary characterization of levofloxacin pharmaceutical cocrystals for dissolution rate enhancement

S Bandari, VR Dronam, BB Eedara - Journal of Pharmaceutical …, 2017 - Springer
… of levofloxacin with stearic acid at 1:1 ratio enhanced the dissolution rate and masked the
bitter taste of levofloxacin whereas saccharin sodium has showed only improved dissolution. …

[HTML][HTML] Exploring the potential of porous silicas as a carrier system for dissolution rate enhancement of artemether

JN Pawar, HR Desai, KK Moravkar, DK Khanna… - asian journal of …, 2016 - Elsevier
… In the present study, dissolution rate enhancement potential of porous silica for ARM is
successfully demonstrated. The results from FTIR chemical imaging, SEM, XRD and DSC …

[PDF][PDF] Enhancement of solubility, dissolution rate and bioavailability of BCS Class II Drugs

V Ramesh, S Meenakshi, N Jyothirmayee… - Int J Pharma Chem …, 2016 - academia.edu
… Various techniques are used for the improvement of the aqueous solubility, dissolution rate,
… and dissolution rates. They require enhancement in solubility and dissolution rate in their …

Poly (2-ethyl-2-oxazoline) as an alternative to poly (vinylpyrrolidone) in solid dispersions for solubility and dissolution rate enhancement of drugs

H Fael, C Ràfols, AL Demirel - Journal of pharmaceutical sciences, 2018 - Elsevier
… studied the dissolution rate of the substance that is continuously released from the surface
exposed to the dissolution media. The IDR is defined as the maximum dissolution rate divided …

Pharmaceutical development of micro and nanocrystals of a poorly water-soluble drug: Dissolution rate enhancement of praziquantel

ADA Silva, MA Sarcinelli… - Journal of Drug Delivery …, 2023 - Elsevier
… In this context, particle size reduction approach can increase solubility and dissolution rate
of drugs, so enhancing their bioavailability. Praziquantel (PZQ) is still the drug of choice for …

Enhancement of mass transfer from particles by local shear‐rate and correlations with application to drug dissolution

Y Wang, JG Brasseur - AIChE Journal, 2019 - Wiley Online Library
… We conclude that shear-rate enhancement to mass and heat transfer from particles
embedded within complex fluid flows, in comparison to mass/heat release within a stagnant fluid, …

New formulation technique for solubility and dissolution rate enhancement of poorly soluble drugs

D Harmalkar, S Godinho, PJ Bhide, L Kumar… - Pharmaceutical …, 2019 - Springer
… The present work was aimed at enhancing the dissolution rate of EBS by formulating it in the
… , it is concluded that LS formulation is a favorable method of EBS solubility enhancement. …