… mammalian genome, and we offer an updated interpretation of the nature of the changes in
methylation patterns … for demethylation or de novo methylation during development, and we …

… (5-methylcytosine, 5mC) is a major form of DNA modification in the mammalian genome …
, DNA methylation is stably maintained in somatic tissues. However, DNA methylation patterns …

… mammalian development. We also discuss new insights gained into the patterning of DNA
methylation … current views of the diverse functions of DNA methylation in genetic diseases. …

… DNA methylation model [9] (Figure 1A). Here, we describe DNA methylation patterns in human
and mouse DNA in the … Moreover, we describe mechanistic features of mammalian DNA …

… of methylation of CpG-rich DNA. We reveal the conservation of large unmethylated valleys
and patterns of DNA methylation … genes across mammals. Finally, using chemical inhibition of …

… Furthermore, the dysregulation of DNA methylation dynamics represents … mammals. This
review discusses the regulation and dysregulation of DNA methylation in plants and mammals. …

… damage, can be accurately estimated using DNA methylation profiles, the foundation of pan-…
pan-mammalian clocks, using 11,754 methylation arrays from our Mammalian Methylation …

… mammalian clocks that measure age in all mammalian species. To address this, we generated
data using 11,754 methylation … of DNA, from 59 tissue-types derived from 185 mammalian …

… DNA methylation profiles closely parallels that of genetics through evolution. Our results
demonstrate that DNA methylation … The publicly available data from our Mammalian Methylation …

… As we have discussed, complex mechanisms have evolved in mammals to ensure that
DNA methylation patterns are faithfully reproduced through cell generations. Among the key …