Riboflavin-targeted drug delivery

M Darguzyte, N Drude, T Lammers, F Kiessling - Cancers, 2020 - mdpi.com
… the riboflavin carrier protein was discovered in the 1960s, the three riboflavin transporters
(… It has been shown that riboflavin transporters and the riboflavin carrier protein are …

Evaluation of riboflavin transporters as targets for drug delivery and theranostics

L Bartmann, D Schumacher, S Von Stillfried… - Frontiers in …, 2019 - frontiersin.org
… of riboflavin has been studied for over a decade, little is known about the riboflavin transporters
… In this study, we investigated the expression pattern of riboflavin transporters in human …

Riboflavin transport mediated by riboflavin transporters (RFVTs/SLC52A) at the rat outer blood-retinal barrier

Y Kubo, S Miki, S Akanuma, K Hosoya - Drug Metabolism and …, 2019 - Elsevier
… In addition, the present findings will be useful in developing an efficient retinal drug delivery
system with riboflavin-conjugated drugs, that will improve the treatment of retinal diseases, …

Influence of riboflavin targeting on tumor accumulation and internalization of Peptostar based drug delivery systems

M Darguzyte, R Holm, J Baier, N Drude… - Bioconjugate …, 2020 - ACS Publications
Riboflavin carrier protein (RCP) and riboflavin transporters (RFVTs) have been reported to …
using riboflavin may enhance tumor accumulation and internalization of drug delivery systems…

Bioengineered riboflavin in nanotechnology

N Beztsinna, M Solé, N Taib, I Bestel - Biomaterials, 2016 - Elsevier
… Due to these features RF attracted researchers in various fields from targeted drug delivery
… , its optical, photosensitizing properties, RF transporter systems and its role in pathologies. …

Riboflavin transport and metabolism in humans

M Barile, TA Giancaspero, P Leone, M Galluccio… - Journal of inherited …, 2016 - Springer
… Therefore, studies on recently identified human plasma membrane riboflavin transporters
are presented, together with those in which still unidentified mitochondrial riboflavin transporter

Blood-to-retina transport of riboflavin via RFVTs at the inner blood-retinal barrier

Y Kubo, S Yahata, S Miki, S Akanuma… - Drug metabolism and …, 2017 - Elsevier
… of the transporter-mediated delivery of riboflavin-conjugated drugs into the retina, … transporter
characterized as multivitamin transporter (SMVT/SLC5A6) is useful for the delivery of drugs

Dual Functions of Riboflavin‐functionalized Poly (lactic‐co‐glycolic acid) Nanoparticles for Enhanced Drug Delivery Efficiency and Photodynamic Therapy in Triple …

W Mekseriwattana, A Phungsom… - Photochemistry and …, 2021 - Wiley Online Library
… cells could be mediated through the interactions with RCP and riboflavin transporters (RFVTs),
native carrier and transporters of Rf. Several studies have previously reported enhanced …

Theoretical Analysis of Riboflavin Adsorption on Hexagonal Boron Nitride for Drug Delivery Applications: Unveiling the Influence of Point Defects

LY Antipina, KY Kotyakova, PB Sorokin - International Journal of …, 2023 - mdpi.com
… the stability of vitamin B2 (riboflavin, Rf) on hexagonal boron … potential as carriers for drug
delivery applications. Employing the … to conceive and refine drug delivery h-BN-based systems. …

[PDF][PDF] Riboflavin-targeted nanomedicines for cancer imaging and drug delivery

Y Tsvetkova - 2018 - d-nb.info
… Flavin mononucleotide (FMN) is a riboflavin derivative that can be exploited to target the
riboflavin transporters (RFTs) and the riboflavin carrier protein (RCP) in cells with high …