Riboflavin-containing telodendrimer nanocarriers for efficient doxorubicin delivery: High loading capacity, increased stability, and improved anticancer efficacy

D Guo, C Shi, X Wang, L Wang, S Zhang, J Luo - Biomaterials, 2017 - Elsevier
… (Rf) as building blocks for efficient doxorubicin (DOX) delivery. Micellar TD nanoparticles (…
drug release and the optimal particle sizes (20–40 nm) for efficient tumor-targeted drug delivery

Development and characterization of the paclitaxel loaded riboflavin and thiamine conjugated carbon nanotubes for cancer treatment

S Singh, NK Mehra, NK Jain - Pharmaceutical Research, 2016 - Springer
… thiamine is facilitated by two transporters of SLC19A family, … drug delivery and targeting eg
folic acid, riboflavin, thiamine, and biotin etc. Thus we attempt to formulate optimized riboflavin

Adaptive regulation of riboflavin transport in heart: effect of dietary riboflavin deficiency in cardiovascular pathogenesis

T Udhayabanu, S Karthi, A Mahesh… - Molecular and Cellular …, 2018 - Springer
… In addition, we have shown that both riboflavin transporters are adaptively regulated upon RF
… , RF transporters could serve as one of the promising route for target-specific drug delivery

Identification of transmembrane protein 237 as a novel interactor with the intestinal riboflavin transporter-3 (RFVT-3): role in functionality and cell biology

S Sabui, VS Subramanian, Q Pham… - American Journal of …, 2019 - journals.physiology.org
… Direct confirmation of interaction between the human riboflavin transporter-3 (hRFVT-3) and
its putative interactor TMEM237 using “1-by-1” yeast two-hybrid (Y2H) interaction assay. A: …

[HTML][HTML] Riboflavin-targeted polymers improve tolerance of paclitaxel while maintaining therapeutic efficacy

M Darguzyte, E Rama, A Rix, J Baier, J Hermann… - … , Biology and Medicine, 2024 - Elsevier
… , it is mainly hypothesized that the riboflavin transporter 3 (RFVT3) is most responsible for
RF … of free PTX 22 , 23 can partially be compensated by our drug delivery system approach. …

Development and Phenotypic Characterisation of a CRISPR/Cas9 Model of Riboflavin Transporter Deficiency in Zebrafish

C Choueiri - 2023 - ruor.uottawa.ca
transporter proteins 2 and 3, encoded by SLC52A2 and … impair riboflavin transporter protein
function and riboflavin … and give rise to riboflavin transporter deficiency (RTD) in humans. …

Riboflavin-conjugated multivalent dendrimer platform for cancer-targeted drug and gene delivery

PT Wong, K Sinniah, SK Choi - Bioactivity of Engineered Nanoparticles, 2017 - Springer
riboflavin (RF) as the targeting ligand. First, we discuss the application of this system for targeted
drug delivery … RF, consisting of RF carrier, RF transporter, and RF binding protein (RFBP…

[PDF][PDF] Riboflavin Functionalized Nanocarriers for Active Targeting of Cancer Cells

M Dargužytė - 2022 - publications.rwth-aachen.de
… the SLC52 transporter family has been identified, consisting of riboflavin transporters: RFVT1/…
The aim of this thesis was to evaluate RF as an active targeting ligand for drug delivery. For …

Riboflavin

AH Merrill Jr, DB McCormick - Present Knowledge in Nutrition, 2020 - Elsevier
… mimic MADD and was found to be improved by supplementation with high doses of
riboflavin and attributed to defects in riboflavin transporters RFVT2/SLC52A2 and RFVT3/SLC52A3. …

In silico investigation on structure–function relationship of members belonging to the human SLC52 transporter family

O Ben Mariem, S Saporiti, U Guerrini… - Proteins: Structure …, 2023 - Wiley Online Library
delivery of drugs with a high affinity for RFVTs. In this work, we propose three-dimensional
structural models for all three human riboflavin transporters … state of riboflavin transporters is …