Probing the combination of erlotinib hydrochloride, an anticancer drug, and human serum albumin: Spectroscopic, molecular docking, and molecular dynamic …

S Shahraki, Z Razmara, HS Delarami… - …, 2023 - Wiley Online Library
Human serum albumin (HSA) is a globular and monomeric protein in plasma that transport
many drugsHuman serum albumin (HSA) and Erlotinib hydrochloride were prepared from …

Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational …

O Dömötör, K Pelivan, A Borics, BK Keppler… - … of Pharmaceutical and …, 2018 - Elsevier
Human serum albumin (HSA) is the most abundant plasma protein with a concentration of
∼… ions, but also for a variety of pharmaceutical compounds. HSA is a single chain globular …

HA/HSA co-modified erlotinibalbumin nanoparticles for lung cancer treatment

Y Shen, W Li - Drug design, development and therapy, 2018 - Taylor & Francis
… Aim of this study was to prepare the hyaluronic acid and human serum albumin modified
erlotinib nanoparticles (ERT-HSA-HA NPs) delivery system by a precipitation method. …

Erlotinib-loaded albumin nanoparticles: A novel injectable form of erlotinib and its in vivo efficacy against pancreatic adenocarcinoma ASPC-1 and PANC-1 cell lines

M Noorani, N Azarpira, K Karimian, H Heli - International journal of …, 2017 - Elsevier
… Cytotoxicity assays after 72 h revealed the potential of ANPs to improve erlotinib toxicity (54%
against 34% of free drug toward ASPC-1 cell line, and 52% … Structure of serum albumin

[HTML][HTML] Quantitative determination of erlotinib in human serum using competitive enzyme-linked immunosorbent assay

Y Yamamoto, T Saita, Y Yamamoto, M Shin - Journal of Pharmaceutical …, 2018 - Elsevier
… the quantification of erlotinib in 50 µL of samples of human serum. Anti-erlotinib serum was
obtained by immunizing mice with an antigen conjugated with bovine serum albumin and 3,4-…

[HTML][HTML] Bovine serum albumin binding study to erlotinib using surface plasmon resonance and molecular docking methods

P Taghipour, M Zakariazadeh, M Sharifi… - Journal of …, 2018 - Elsevier
… delivery in blood. Therefore, we aim to study BSA interaction with erlotinib as an anticancer
drug … Heart-shaped structure of bovine serum albumin (BSA) is very similar to human serum

Erlotinib

AA Abdelgalil, HM Al-Kahtani, FI Al-Jenoobi - Profiles of Drug Substances …, 2020 - Elsevier
… estimation of erlotinib hydrochloride in its bulk drug substance and in pharmaceutical dosage
… and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma

[PDF][PDF] Serum albumin is a strong predictor of survival in patients with advanced-stage non-small cell lung cancer treated with erlotinib

O Fiala, M Pesek, J Finek, J Racek, M Minarik… - …, 2016 - scholar.archive.org
… or molecular predictors of response to erlotinib have been validated. The … serum albumin
with outcomes in a large cohort of patients with advanced-stage NSCLC treated with erlotinib. …

Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma

M Kamali, TJ Webster, A Amani, MR Hadjighassem… - Life Sciences, 2023 - Elsevier
… The aim of this study was to prepare folate-targeted Erlotinib loaded human serum albumin
… for high drug doses [3]. Human serum albumin (HSA), as the most abundant protein in the …

… of a tyrosine kinase inhibitor erlotinib with a model transport protein in the presence of quercetin: A drug–protein and drugdrug interaction investigation using multi …

TA Wani, MM Alanazi, NA Alsaif, AH Bakheit, S Zargar… - Molecules, 2022 - mdpi.com
… , pharmacodynamics, and toxicity of drugs [2]. The two most common serum albumin used
as model transport proteins are BSA and HSA (human serum albumin). There is almost 75.6% …