The impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: a quantitative synthesis

P Rogliani, MG Matera, J Ora, M Cazzola… - International journal of …, 2017 - Taylor & Francis
Dual bronchodilation therapy is the cornerstone for … bronchodilation and, thus, reduce the
risk of adverse events (AEs). Citation8 Unfortunately, the doses of each single bronchodilator

[HTML][HTML] Role of dual bronchodilators in COPD: a review of the current evidence for indacaterol/glycopyrronium

JH Ficker, KF Rabe, T Welte - Pulmonary pharmacology & therapeutics, 2017 - Elsevier
… combining long-acting bronchodilators in the management of … for combining two classes of
bronchodilators (a long-acting β 2 -… related to combined bronchodilator therapy for COPD, and …

[HTML][HTML] Dual bronchodilation and exacerbations of COPD

M Cazzola, J Ora, E Puxeddu - Journal of Thoracic Disease, 2016 - ncbi.nlm.nih.gov
… In particular, we would like to know if dual bronchodilation is effective in … of dual bronchodilation
based on COPD phenotype (21). The prescription of dual bronchodilator therapy should …

Dual bronchodilation with tiotropium/olodaterol further reduces activity-related breathlessness versus tiotropium alone in COPD

F Maltais, JL Aumann, AM Kirsten… - European …, 2019 - Eur Respiratory Soc
therapy [20]. These observations do not mean that patients are worse with … that dual
bronchodilation improves patient-reported breathlessness in COPD compared with bronchodilator

Triple versus dual inhaler therapy in moderate‐to‐severe COPD: A systematic review and meta‐analysis of randomized controlled trials

Y Zayed, M Barbarawi, B Kheiri… - The clinical …, 2019 - Wiley Online Library
therapy was associated with a reduction of moderate‐to‐severe COPD exacerbations,
improved lung function and improved quality of life when compared to dual inhaler therapy but …

Single inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind …

D Singh, A Papi, M Corradi, I Pavlišová, I Montagna… - The Lancet, 2016 - thelancet.com
… Few data are available for the efficacy of “triple therapy” with two long-acting bronchodilators
and an inhaled corticosteroid in chronic obstructive pulmonary disease (COPD). We …

Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial

S Pascoe, N Barnes, G Brusselle… - The Lancet …, 2019 - thelancet.com
… with blood eosinophil count, compared with a non-ICS dual long-acting bronchodilator (umeclidinium–vilanterol
n=2070). The moderate and severe exacerbation rate ratio for triple …

Double bronchodilation in chronic obstructive pulmonary disease: a crude analysis from a systematic review

JL Lopez-Campos, C Calero-Acuña… - … Journal of Chronic …, 2017 - Taylor & Francis
… Studies comparing double bronchodilation therapy with an inhaled corticosteroid and LABA
… of the fixed-dose dual bronchodilator combination tiotropiumolodaterol for patients with …

[Retracted] Study on the Management of the Health Status of Patients with Stable Chronic Obstructive Pulmonary Disease Treated with Double Bronchodilator

W Wang, Q Yang, Q Xun, X Ye - … ‐Based Complementary and …, 2022 - Wiley Online Library
bronchodilator therapy and influencing factors. Methods. The patients with stable COPD who
used double bronchodilators … between the treatment of dual bronchodilators in patients with …

Dual bronchodilation response by exacerbation history and eosinophilia in the FLAME study

A Papi, K Kostikas, JA Wedzicha… - American journal of …, 2018 - atsjournals.org
Discussion Among patients with a nodule size 8 mm or larger or nodule size 4 mm or larger
on baseline screen in the NLST, we found that the Brock model was most accurate for …