Kilohertz frequency nerve block enhances anti-inflammatory effects of vagus nerve stimulation

YA Patel, T Saxena, RV Bellamkonda, RJ Butera - Scientific reports, 2017 - nature.com
… , called block efficacy, for evaluating the status of KES nerve block. This approach enables
quantitative validation and evaluation of the effects of KES nerve block. Quantification of block

Effect of vagal nerve blockade on moderate obesity with an obesity-related comorbid condition: the ReCharge study

JM Morton, SN Shah, BM Wolfe, CM Apovian, CJ Miller… - Obesity surgery, 2016 - Springer
Background Vagal nerve blockade (vBloc) therapy was shown to be a safe and effective
treatment for moderate to severe obesity. This report summarizes the safety and efficacy of …

Anodal block permits directional vagus nerve stimulation

U Ahmed, YC Chang, M Cracchiolo, MF Lopez… - Scientific reports, 2020 - nature.com
… has been reported, but without documentation of afferent effects or of evoked activation of
nerve fibers. It is therefore unclear whether anodal block in VNS is a viable mechanism to …

Role of the vagus nerve in the development and treatment of diet‐induced obesity

G De Lartigue - The Journal of physiology, 2016 - Wiley Online Library
… , and known mechanisms of vagal nerve stimulation and vagal blockade will be discussed.
… performed, looking at the effect of chronic cervical vagus nerve stimulation on metabolism (…

Selective neuromodulation of the vagus nerve

A Fitchett, S Mastitskaya, K Aristovich - Frontiers in neuroscience, 2021 - frontiersin.org
… side-effects. It has the potential to achieve greater specificity and provide crucial information
about vagal nerve physiology. Anodal block achieves strong side-effect mitigation too, but is …

Intermittent vagal nerve block for improvements in obesity, cardiovascular risk factors, and glycemic control in patients with type 2 diabetes mellitus: 2-year results of …

SA Shikora, J Toouli, MF Herrera, B Kulseng… - Obesity surgery, 2016 - Springer
… This investigation has demonstrated that the beneficial effects of an intermittent VBLOC seen
after 12 months of therapy were maintained at 24 months. The average EWL at 12 months …

Cardiovascular autonomic effects of vagus nerve stimulation

I Garamendi-Ruiz, JC Gómez-Esteban - Clinical Autonomic Research, 2019 - Springer
… To evaluate the effect of vagus nerve stimulation therapy on the autonomic nervous system,
… the left vagal branch predisposes the heart to conduction block at the atrioventricular node. …

Two-year outcomes of vagal nerve blocking (vBloc) for the treatment of obesity in the ReCharge trial

CM Apovian, SN Shah, BM Wolfe, S Ikramuddin… - Obesity surgery, 2017 - Springer
… Intermittent vagal blockade using the vBloc device for 24 months in the ReCharge Trial …
Vagal block treated participants achieved 21 % EWL (8 % TWL) at 24 months, similar to the …

A review of vagus nerve stimulation as a therapeutic intervention

RL Johnson, CG Wilson - Journal of inflammation research, 2018 - Taylor & Francis
… Citation61 Another potential proposed mechanism for the effect of VNS on weight is reduced
… However, selective blockade of vagal fibers using different electrical stimulation parameters …

Chronic vagal nerve stimulation exerts additional beneficial effects on the beta-blocker-treated failing heart

M Li, C Zheng, T Kawada, M Inagaki, K Uemura… - The journal of …, 2019 - Springer
… If VNS treatment exerts benefits mainly through its anti-beta-adrenergic action, beta-blockade
should cover these effects. Clinical study is difficult to verify this hypothesis. There is no …