[HTML][HTML] … treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR-mutated …
… -mutant NSCLC, the treatment decision should ideally be based on assessing differences
in effectiveness of each EGFR TKI against the trade-off of differences in treatment-related …
in effectiveness of each EGFR TKI against the trade-off of differences in treatment-related …
The efficacy of first-line tyrosine kinase inhibitors combined with co-medications in Asian patients with EGFR mutation non-small cell lung cancer
… of glucocorticoids may reduce the efficacy of EGFR-TKIs in such patients. … efficacy of three
EGFR-TKIs as first-line treatment in patients with advanced NSCLC harboring EGFR mutations…
EGFR-TKIs as first-line treatment in patients with advanced NSCLC harboring EGFR mutations…
Cost-effectiveness analysis of EGFR mutation testing in patients with non-small cell lung cancer (NSCLC) with gefitinib or carboplatin–paclitaxel
O Arrieta, P Anaya, V Morales-Oyarvide… - The European Journal of …, 2016 - Springer
… the cost-effectiveness of an EGFR mutation testing strategy … with gefitinib for patients harbouring
an EGFR mutation in … the EGFR mutation status, and CTX for those patients with EGFR-wt…
an EGFR mutation in … the EGFR mutation status, and CTX for those patients with EGFR-wt…
Efficacy and safety of afatinib in a Chinese population with advanced lung adenocarcinoma with sensitive EGFR mutations
S Wang, P Xing, K Yang, X Hao, D Ma, Y Mu… - Thoracic …, 2019 - Wiley Online Library
… EGFR mutations in our study may not have been large enough to confirm the efficacy of
afatinib in these patients. A larger sample of patients with uncommon EGFR mutations are …
afatinib in these patients. A larger sample of patients with uncommon EGFR mutations are …
Safety of gefitinib in non-small cell lung cancer treatment
EHC Hsiue, JH Lee, CC Lin… - Expert opinion on drug …, 2016 - Taylor & Francis
… EGFR mutations [Citation11]. This review summarizes gefitinib’s pharmacological property,
clinical efficacy, … supports the efficacy and tolerability of gefitinib in treating EGFR mutation-…
clinical efficacy, … supports the efficacy and tolerability of gefitinib in treating EGFR mutation-…
Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label …
YL Wu, Y Cheng, X Zhou, KH Lee, K Nakagawa… - The Lancet …, 2017 - thelancet.com
… its efficacy and safety with that of the reversible EGFR tyrosine kinase inhibitor gefitinib in …
patients with wild-type EGFR or unknown EGFR mutation status had a shorter progression-free …
patients with wild-type EGFR or unknown EGFR mutation status had a shorter progression-free …
Clinical efficacy evaluation of tyrosine kinase inhibitors for non-adenocarcinoma lung cancer patients harboring EGFR-sensitizing mutations
X Song, Z Wang - OncoTargets and therapy, 2017 - Taylor & Francis
… Citation1 In the last decade, the discovery of epidermal growth factor receptor (EGFR) and
the remarkable efficacy of tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations …
the remarkable efficacy of tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations …
EGFR-TKIs plus chemotherapy demonstrated superior efficacy than EGFR-TKIs alone as first-line setting in advanced NSCLC patients with EGFR mutation and BIM …
S Liu, Y He, T Jiang, S Ren, F Zhou, C Zhao, X Li… - Lung Cancer, 2018 - Elsevier
… of EGFR-TKIs with chemotherapy showed a better efficacy and acceptable side effects
comparing with EGFR-TKIs alone in advanced NSCLCs with activating EGFR mutation and BIM …
comparing with EGFR-TKIs alone in advanced NSCLCs with activating EGFR mutation and BIM …
… Survival in a Randomized Study That Compared Dacomitinib With Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer and EGFR-Activating Mutations
TS Mok, Y Cheng, X Zhou, KH Lee… - Journal of Clinical …, 2018 - ascopubs.org
… with gefitinib in patients with NSCLC and EGFR mutations … the efficacy and safety of dacomitinib
versus gefitinib as first-… metastatic NSCLC with EGFR activating mutations. The primary …
versus gefitinib as first-… metastatic NSCLC with EGFR activating mutations. The primary …
[HTML][HTML] Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial
L Paz-Ares, EH Tan, K O'Byrne, L Zhang, V Hirsh… - Annals of …, 2017 - Elsevier
… gefitinib with erlotinib and found no difference in efficacy and … first-line EGFR-targeted TKIs
in patients with EGFR mutation-… We hypothesise that the efficacy benefits with afatinib reflect …
in patients with EGFR mutation-… We hypothesise that the efficacy benefits with afatinib reflect …