[HTML][HTML] Safety and efficacy of first-line dacomitinib in Asian patients with EGFR mutation-positive non-small cell lung cancer: Results from a randomized, open-label …

Y Cheng, TS Mok, X Zhou, S Lu, Q Zhou, J Zhou, Y Du… - Lung Cancer, 2021 - Elsevier
… had a dose reduction showed that efficacy was maintained in patients who had … gefitinib
in the Asian population of ARCHER 1050 [15]. This report describes an analysis of the efficacy

Which is better EGFR-TKI followed by osimertinib: afatinib or gefitinib/erlotinib?

M Tamiya, A Tamiya, H Suzuki, K Moriizumi… - Anticancer …, 2019 - ar.iiarjournals.org
… Therefore, we analyzed the efficacy of these … EGFR mutations in EGFR mutation-positive
NSCLC has potential clinical implications since different EGFR TKIs have varying effectiveness

Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer

RD Petty, A Dahle-Smith, DAJ Stevenson… - Journal of Clinical …, 2017 - ascopubs.org
Gefitinib trial tumors was conducted to compare efficacy of gefitinib with that of placebo
according to EGFR … adenocarcinoma in which EGFR mutation and KRAS mutation, respectively, …

Gefitinib Versus Adjuvant Chemotherapy in Patients with Stage II-IIIA Non–Small-Cell Lung Cancer Harboring Positive EGFR Mutations: A Single-Center …

H Xie, H Wang, L Xu, M Li, Y Peng, X Cai, Z Feng… - Clinical Lung Cancer, 2018 - Elsevier
… of gefitinib to chemotherapy exists regarding the postoperative adjuvant therapy of EGFR
mutation… study to assess the efficacy of adjuvant gefitinib versus adjuvant chemotherapy (AC) in …

Study of gefitinib and pemetrexed as first-line treatment in patients with advanced non-small cell lung cancer harboring EGFR mutation

C An, J Zhang, H Chu, C Gu, F Xiao, F Zhu… - Pathology & Oncology …, 2016 - Springer
efficacy in patients treated with gefitinib. The research was designed to evaluate the efficacy
and safety of pemetrexed combined with gefitinib as … harboring a sensitive EGFR mutation. …

… of the effect of proton pump inhibitors on the efficacy of dacomitinib and gefitinib in patients with advanced non-small cell lung cancer and EGFR-activating mutations

J Li, D Nickens, K Wilner, W Tan - Oncology and Therapy, 2021 - Springer
… As a result, the use of PPIs in patients with advanced NSCLC with activating EGFR
mutations is unlikely to impact dacomitinib or gefitinib treatment efficacy despite decreased …

Impact of EGFR genotype on the efficacy of osimertinib in EGFR tyrosine kinase inhibitor-resistant patients with non-small cell lung cancer: a prospective …

S Igawa, T Ono, M Kasajima, M Ishihara… - Cancer Management …, 2019 - Taylor & Francis
… NSCLC harboring EGFR mutation. Regarding the efficacy of EGFR-TKI, we previously
reported the association between smoking status and efficacy of EGFR-TKI including gefitinib and …

[HTML][HTML] … of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in targeted therapy of lung squamous cell carcinoma patients with EGFR mutation …

J Zhuang, Y Yu, Z Li, S Lu - Oncotarget, 2017 - ncbi.nlm.nih.gov
EGFR mutationsEGFR-TKIs in EGFR mutated LSCC patients. In this study, we performed
a pooled analysis to evaluate the efficacy of EGFR-TKIs in LSCC patients with EGFR mutations

[HTML][HTML] Clinical efficacy of icotinib in lung cancer patients with different EGFR mutation status: a meta-analysis

J Qu, YN Wang, P Xu, DX Xiang, R Yang, W Wei… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… The efficacy of EGFR-TKIs has been shown to be associated with the EGFR mutation
status, especially exon 19 deletion (19Del) and exon 21 L858R mutation. Therefore, a meta-…

Effectiveness of afatinib after ineffectiveness of gefitinib in an advanced lung adenocarcinoma patient with a single EGFR exon 20 S768I mutation: a case report

H Duan, Y Peng, H Cui, Y Qiu, Q Li, J Zhang… - OncoTargets and …, 2018 - Taylor & Francis
… S768I mutation received first- and second-generation EGFR-TKIs successively, and the
response was completely different. The S768I mutation is a rare subset of EGFR mutants located …