Real-world effectiveness of voxelotor for treating sickle cell disease in the US: a large claims data analysis
… This study uses real-world evidence to assess voxelotor’s effectiveness in SCD patients in
typical clinical practice from 2019 to 2021 using a national medical claims database (N = 3128…
typical clinical practice from 2019 to 2021 using a national medical claims database (N = 3128…
Voxelotor: a novel treatment for sickle cell disease
LB Herity, DMM Vaughan… - Annals of …, 2021 - journals.sagepub.com
… to assess safety and establish preliminary efficacy of voxelotor. Efficacy was evaluated in the
… randomized to receive 28 days of voxelotor 500 mg/d (n = 10), voxelotor 700 mg/d (n = 12), …
… randomized to receive 28 days of voxelotor 500 mg/d (n = 10), voxelotor 700 mg/d (n = 12), …
Safety and efficacy of voxelotor in pediatric patients with sickle cell disease aged 4 to 11 years
JH Estepp, R Kalpatthi, G Woods… - Pediatric blood & …, 2022 - Wiley Online Library
… ‐dose study to evaluate the pharmacokinetics, efficacy, and safety of voxelotor—a first‐in‐class …
Initial findings from a cohort of 45 patients aged 4 to 11 years who received voxelotor …
Initial findings from a cohort of 45 patients aged 4 to 11 years who received voxelotor …
Voxelotor for the treatment of sickle cell disease
M Vissa, E Vichinsky - Expert Review of Hematology, 2021 - Taylor & Francis
… sufficient evidence of the safety and efficacy of voxelotor in increasing hemoglobin
concentration and decreasing hemolysis in patients with sickle cell disease ages 12 and older. A …
concentration and decreasing hemolysis in patients with sickle cell disease ages 12 and older. A …
[HTML][HTML] Real-world effectiveness of voxelotor for treating sickle cell disease in the US
AU Zaidi, T Lipato, OA Alvarez, A Lonshteyn… - Blood, 2020 - Elsevier
… the real-world effectiveness of voxelotor based on data … ≥12 years and receiving voxelotor
from December 2019 to May … the real-world effectiveness of voxelotor based on data during …
from December 2019 to May … the real-world effectiveness of voxelotor based on data during …
A phase 3 randomized trial of voxelotor in sickle cell disease
E Vichinsky, CC Hoppe, KI Ataga… - … England Journal of …, 2019 - Mass Medical Soc
… , we compared the efficacy and safety of two dose levels of voxelotor (1500 mg and 900 mg,
administered orally once daily) with placebo in persons with sickle cell disease. The primary …
administered orally once daily) with placebo in persons with sickle cell disease. The primary …
Real‐world data on voxelotor to treat patients with sickle cell disease
K Muschick, T Fuqua, C Stoker‐Postier… - European Journal of …, 2022 - Wiley Online Library
… provides the largest single-institution cohort analysis of patients with SCD treated with
voxelotor and provides helpful insight for patients and clinicians regarding real-world efficacy. …
voxelotor and provides helpful insight for patients and clinicians regarding real-world efficacy. …
[HTML][HTML] Efficacy and safety of voxelotor in sickle cell disease: a systematic review
… Voxelotor (GBT440) is a hemoglobin modulator that prevents … evaluate the efficacy and safety
of voxelotor in SCD patients. … to evaluate the efficacy and safety of voxelotor in SCD patients…
of voxelotor in SCD patients. … to evaluate the efficacy and safety of voxelotor in SCD patients…
[HTML][HTML] Efficacy and safety of voxelotor in adolescents and adults with sickle cell disease: HOPE trial 72-week analysis
J Howard, KI Ataga, RC Brown, M Achebe, V Nduba… - Blood, 2020 - Elsevier
… demonstrated that treatment with voxelotor 1500 mg resulted in … the evaluation of efficacy
and safety of voxelotor 1500 mg at … the evaluation of efficacy and safety of voxelotor 1500 mg at …
and safety of voxelotor 1500 mg at … the evaluation of efficacy and safety of voxelotor 1500 mg at …
[HTML][HTML] Comparing the safety and efficacy of L-glutamine, voxelotor, and crizanlizumab for reducing the frequency of vaso-occlusive crisis in sickle cell disease: a …
MH Dick, A Abdelgadir, VV Kulkarni, H Akram… - Cureus, 2022 - ncbi.nlm.nih.gov
… , however, understanding the effectiveness and tolerability of these medicaments will … of
voxelotor, l-glutamine, and crizanlizumab on SCD patients, specifically their response, efficacy, …
voxelotor, l-glutamine, and crizanlizumab on SCD patients, specifically their response, efficacy, …
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